Our Publications

Eskandari, R., Milkovich, S., Kamar, F., Welsh, D. G., Goldman, D., Ellis, C. G., & Diop, M. (2024, December). Non-invasive point-of-care optical technique for continuous in vivo assessment of microcirculatory function: Application to a preclinical model of early sepsis. The FASEB Journal, 38(23), e70204.

Wang, Q., Pan, M., Kreiss, L., Samaei, S., Carp, S. A., Johansson, J. D., Zhang, Y., Wu, M., Horstmeyer, R., Diop, M., & Li, D. D. U. (2024). A comprehensive overview of diffuse correlation spectroscopy: theoretical framework, recent advances in hardware, analysis, and applications. NeuroImage, 120793.

Mawdsley, L.¹, Eskandari, R.¹, Kamar, F., Rajaram, A., Yip, L. C. M., Abayomi, N., Milkovich, S., St. Lawrence, K., Carson, J. J. L., Ellis, C. G., & Diop, M. (2024, August). In vivo optical assessment of cerebral and skeletal muscle microvascular response to phenylephrine. FASEB BioAdvances, 6(9), 390.

Ioussoufovitch, S., & Diop, M. (2024). Time-domain diffuse optical imaging technique for monitoring rheumatoid arthritis disease activity: experimental validation in tissue-mimicking finger phantoms. Physics in medicine and biology.

Kamar, F., Shoemaker, L. N., Eskandari, R., Milej, D., Drosdowech, D., Murkin, J. M., St. Lawrence, K., Chui, J., & Diop, M. (2024). Assessing changes in regional cerebral hemodynamics in adults with a high-density full-head coverage time-resolved near-infrared spectroscopy device. Journal of Biomedical Optics, 29(S3), S33302-S33302.

Li, N. C., Ioussoufovitch, S., & Diop, M. (2024). HyperTRCSS: A hyperspectral time-resolved compressive sensing spectrometer for depth-sensitive monitoring of cytochrome-c-oxidase and blood oxygenation. Journal of Biomedical Optics, 29(1), 015002-015002.

S. Ioussoufovitch, L. Morrison, L. Desjardins, J. Hadway, K. St. Lawrence, T.-Y. Lee, F. Beier, M. Diop, " Quantification of joint blood flow by dynamic contrast-enhanced near-infrared spectroscopy: Application to monitoring disease activity in a rat model of rheumatoid arthritis", Journal of Biomedical Optics, 25(1), 015003 (2020).

A. Abdalmalak, D. Milej, L. C. M. Yip, A. R. Khan, M. Diop, A. M. Owen, K. St Lawrence, "Assessing time-resolved fNIRS for brain-computer interface applications of mental communication", Frontiers in Neuroscience, 14, 105 (2020).

A. Abdalmalak, D. Milej, D. J. Cohen, U. Anazodo, T. Ssali, M. Diop, A. M. Owen, K. St Lawrence, "Using fMRI to investigate the potential cause of inverse oxygenation reported in fNIRS studies of motor imagery", Neuroscience Letters, 714, 1346072 (2020).

D. Milej, L. He, A. Abdalmalak, W. B. Baker, U. C Anazodo, M. Diop, S. Dolui, V. C. Kavuri, W. Pavlosky, L. Wang, R. Balu, J. A. Detre, O. Amendolia, F. Quattrone, W. A. Kofke, A. G. Yodh, K. St Lawrence, " Quantification of cerebral blood flow in adults by contrast-enhanced near-infrared spectroscopy: Validation against MRI", Journal of Cerebral Blood Flow & Metabolism, 0271678X19872564.

M. Kewin, A. Rajaram, D. Milej, A. Abdalmalak, L. Morrison, M. Diop, K. St Lawrence, "Evaluation of hyperspectral NIRS for quantitative measurements of tissue oxygen saturation by comparison to time-resolved NIRS", Biomedical optics express, 10(9), 4789-4802 (2019).

M. Khalid, D. Milej, A. Rajaram, A. Abdalmalak, L. Morrison, M. Diop, K. St Lawrence, "Development of a stand-alone DCS system for monitoring absolute cerebral blood flow", Biomedical optics express, 10(9), 4607-4620 (2019).

D. R Busch, R. Balu, W. Baker, W. Guo, L. He, M. Diop, D. Milej, V. Kavuri, O. Amendolia, K. St Lawrence, A. G Yodh, W. A. Kofke, "Detection of Brain Hypoxia Based on Non-invasive Optical Monitoring of Cerebral Blood Flow with Diffuse Correlation Spectroscopy", Neurocritical Care, 30 (1), 72-80 (2019).

L. He, W. B. Baker, D. Milej, V. C. Kavuri, R. C. Mesquita, D. R. Busch, K. Abramson, Y. J. Jiang, M. Diop, K. St. Lawrence, O. Amendolia, F. Quattrone, R. Balu, W. A. Kofke, and A. G. Yodh, “Noninvasive continuous optical monitoring of absolute cerebral blood flow in critically ill adults” Neurophotonics 5 (4), 045006 (2018).

A. Rajaram, G. Bale, M. Kewin, I. Tachtsidis, K. St. Lawrence, M. Diop, " Simultaneous monitoring of cerebral perfusion and cytochrome c oxidase by combining broadband near-infrared spectroscopy and diffuse correlation spectroscopy", Biomedical Optics Express, 9 (6), 2588-2603 (2018).

A. Abdalmalak, D. Milej, L. Norton, D. B. Debicki, T. Gofton, M. Diop, A. M. Owen, K. St. Lawrence, "Single-session Communication with a Locked-In Patient by Functional Near-Infrared Spectroscopy", Neurophotonics, 4 (4), 040501 (2017).

P. McLachlan, J. Kishimoto, S. de Ribeaupierre, D.S. C. Lee, M. Diop, K. St Lawrence, "Investigating the Effects of Cerebrospinal Fluid Removal on Cerebral Blood Flow and Oxidative Metabolism in Infants with Post-Hemorrhagic Ventricular Dilatation", Pediatric Research, 82(4), 634-641 (2017).

D. Milej, A. Abdalmalak, L. Desjardins, H. Ahmed, T.-Y. Lee, M. Diop, and K. St Lawrence, "Quantification of blood-brain barrier permeability by dynamic contrast-enhanced NIRS", Scientific Reports 7(1), 1702 (2017).

A. Abdalmalak, D. Milej, M. Diop, M. Shokouhi, L. Naci, A. Owen, and K. St Lawrence, "Can time-resolved NIRS provide the sensitivity to detect brain activity during motor imagery consistently?", Biomedical Optics Express 8 (4), 2162-2172 (2017).

D. Milej, A. Abdalmalak, M. Diop, P. McLachlan, A. Liebert, and K. St. Lawrence, "A subtraction-based approach for enhancing the depth sensitivity of time-resolved NIRS", Biomedical Optics Express 7(11), 4514-4526 (2016).

A. Rajaram, S. Ioussoufovitch, L. B. Morrison, K. St Lawrence, T.-Y. Lee, Y. Bureau, and M. Diop, "Joint blood flow is more sensitive to inflammatory arthritis than oxyhemoglobin, deoxyhemoglobin, and oxygen saturation", Biomedical Optics Express 7(10), 3843-3854 (2016).

K. Verdecchia, M. Diop, A. Lee, L. B. Morrison, T.-Y. Lee, and K. St Lawrence, "Assessment of a multi-layered diffuse correlation spectroscopy method for monitoring cerebral blood flow in adults", Biomedical Optics Express 7(9), 3659-3674 (2016).

D. Milej, A. Abdalmalak, D. Janusek, M. Diop, A. Liebert, and K. St. Lawrence, " Time-resolved subtraction method for measuring optical properties of homogeneous turbid media", Applied Optics 55 (7), 1507-1513 (2016).

K. Verdecchia, M. Diop, L. B. Morrison, T.-Y. Lee, and K. St. Lawrence, "Assessment of the best flow model to characterize diffuse correlation spectroscopy data acquired directly on the brain", Biomedical Optics Express 6(11), 4288-4301 (2015).

M. Diop, J. Kishimoto, V. Toronov, D. S. C. Lee, and K. St Lawrence, "Development of a combined broadband near-infrared and diffusion correlation system for monitoring cerebral blood flow and oxidative metabolism in preterm infants", Biomedical Optics Express 6(10), 3907-3918 (2015)

M. F. Bakhsheshi, M. Diop, L. B. Morrison, K. St Lawrence, and T.-Y. Lee, " Coupling of cerebral blood flow and oxygen consumption during hypothermia in newborn piglets as measured by time-resolved near-infrared spectroscopy: a pilot study", Neurophotonics 2(3), 035006 (2015).

M. Diop, E. Wright, V. Toronov, T.-Y. Lee, and K. St Lawrence, "Improved light collection and wavelet de-noising enable quantification of cerebral blood flow and oxygen metabolism by a low-cost off-the-shelf spectrometer", Journal of Biomedical Optics 19(5), 057007 (2014).

M. Fazel Bakhsheshi, M. Diop, T.-Y. Lee, and K. St Lawrence, "Monitoring Brain Temperature by Time-Resolved Near-Infrared Spectroscopy: A Pilot Study", Journal of Biomedical Optics 19(5), 057005 (2014).

J. T. Elliott, M. Diop, L. B. Morrison, C. D. d'Esterre, T.-Yim Lee, K. St. Lawrence, "Quantifying cerebral blood flow in an adult pig ischemia model by a depth-resolved dynamic contrast-enhanced optical method", NeuroImage 94, 303-311 (2014).

K. Tichauer, M. Diop, J. Elliott, K. Samkoe, T. Hasan, K. St Lawrence, B. Pogue, "Accounting for pharmacokinetic differences in dual-tracer receptor density imaging", Physics in Medicine and Biology 59(10), 2341–2351 (2014). This article was featured by the journal.

M. Diop and K. St. Lawrence, "Improving the depth sensitivity of time-resolved measurements by extracting the distribution of times-of-flight", Biomedical Optics Express 4(3), 447–459 (2013).

K. St Lawrence, K. Verdecchia, J. T. Elliott, K. Tichauer, M. Diop, L. Hoffman, and T.-Y. Lee, "Kinetic model optimization for characterizing tumour physiology by dynamic contrast-enhanced near-infrared spectroscopy", Physics in Medicine and Biology 58(5), 1591–1604 (2013).

K. Verdecchia, M. Diop, and K. St Lawrence, "Quantifying the cerebral metabolic rate of oxygen by combining diffuse correlation spectroscopy and time-resolved near-infrared spectroscopy", Journal of Biomedical Optics 18(2), 027007 (2013).

R. Arora, M. Ridha, D. Lee, J. Elliott, M. Diop, H. Rosenberg, T.-Y. Lee, and K. St Lawrence, "Preservation of the metabolic rate of oxygen in preterm infants during indomethacin therapy for closure of the ductus arteriosus", Pediatric Research 73(6), 713-718 (2013).

J. T. Elliott, D. Milej, A. Gerega, W. Weigl, M. Diop, L. B. Morrison, T.-Y. Lee, A. Liebert, and K. St Lawrence, "Variance of time-of-flight distribution is sensitive to cerebral blood flow as demonstrated by ICG bolus-tracking measurements in adult pigs", Biomedical Optics Express 4(2), 206–218 (2013).

J. T. Elliott, E. Wright, K. M. Tichauer, M. Diop, L. B. Morrison, B. W. Pogue, T.-Y. Lee, K. St. Lawrence, "Arterial input function of an optical tracer for dynamic contrast enhanced imaging can be determined from pulse oximetry oxygen saturation measurements", Physics in Medicine and Biology 57(24), 8285 (2012).

H. Z. Yeganeh, V. Toronov, J. T. Elliott, M. Diop, T.-Y. Lee, and K. St Lawrence, "Broadband continuous-wave technique to measure baseline values and changes in the tissue chromophore concentrations", Biomedical Optics Express 3(11), 2761-2770 (2012).

J. T. Elliott, M. Diop, T.-Y. Lee, and K. St Lawrence, "Model-independent dynamic constraint to improve the optical reconstruction of regional kinetic parameters", Optics Letters 37(13), 2571-2573 (2012). Subsequently selected and published in the Virtual Journal for Biomedical Optics 7(9), Aug. 28, 2012.

M. Diop and K. St Lawrence, "Deconvolution method for recovering the photon time-of-flight distribution from time-resolved measurements", Optics Letters 37(12), 2358-2360 (2012). Subsequently selected and published in the Virtual Journal for Biomedical Optics 7(8), Aug. 2, 2012.

M. Diop, K. Verdecchia, T.-Y. Lee, and K. St Lawrence, "Calibration of diffuse correlation spectroscopy with a time-resolved near-infrared technique to yield absolute cerebral blood flow measurements", Biomedical Optics Express 2(7), 2068-2081 (2011).

J. A. Cooper, K. M. Tichauer, M. Boulton, J. T. Elliott, M. Diop, M. Arango, T.-Y. Lee, and K. St Lawrence, "Continuous monitoring of absolute cerebral blood flow by near-infrared spectroscopy during global and focal temporary vessel occlusion", J. Appl. Physiol. 110(6), 1691-1698 (2011).

K. M. Tichauer, M. Migueis, F. Leblond, J. T. Elliott, M. Diop, K. St Lawrence, and T.-Y. Lee, "Depth resolution and multiexponential lifetime analyses of reflectance-based time-domain fluorescence data", Applied Optics 50(21), 3962-3972 (2011).

M. Diop, K. Tichauer, J. Elliott, M. Migueis, T.-Y. Lee, and K. St Lawrence, "Comparison of time-domain and continuous-wave near-infrared spectroscopy techniques of measuring cerebral blood flow in piglets", J. Biomed. Opt. 15(5), 057004 (2010).

J. T. Elliott, M. Diop, K. Tichauer, T. Y. Lee, and K. St Lawrence, "Quantitative measurement of cerebral blood flow in a juvenile porcine model by depth-resolved near-infrared spectroscopy", J. Biomed. Opt. 15(3), 037014 (2010).

M. Diop, J. Elliott, K. Tichauer, T.-Y. Lee, and K. St Lawrence, "A Broadband Continuous-Wave Multi-Channel Near Infrared System for Measuring Regional Cerebral Blood Flow and Oxygen Consumption in Newborn Piglets", Review of Scientific Instruments 80, 054302 (2009). Subsequently selected and published in the Virtual Journal of Biological Physics Research 17(10), May 15, 2009.

G. Bale, A. Rajaram, M. Kewin, L. Morrison, A. Bainbridge, L. Liu, U. Anazodo, M. Diop, K. St. Lawrence, I. Tachtsidis, "Multimodal measurements of brain tissue metabolism and perfusion in a neonatal model of hypoxic-ischaemic injury," Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 1107414 (2019/07/11).

H.Wang, P. Omidi, J. JL Carson, M. Diop, "Holographic camera for non-contact measurement of nanoscale surface heights", Proc. SPIE 10944, Practical Holography XXXIII: Displays, Materials, and Applications, 109440X (2019/03/01).

D. Cohen, M. Diop, "In silico investigation of near-infrared light propagation in the joints of the human hand", Proc. SPIE 10874, Optical Tomography and Spectroscopy of Tissue XIII, 1087427 (2019/03/01).

P. Omidi, H. Wang, M. Diop, J. JL Carson, "Algorithm for phase-displacement conversion from reflection digital holographic interferometry", Proc. SPIE 10944, Practical Holography XXXIII: Displays, Materials, and Applications, 109440Q (2019/03/01).

S. Ioussoufovitch, L. B. Morrison, L. Desjardins, J. A. Hadway, K. St Lawrence, T.-Y. Lee, F. Beier, M. Diop, " Quantifying joint blood flow in a rat model of rheumatoid arthritis with dynamic contrast-enhanced near-infrared spectroscopy", Proc. SPIE 10874, Optical Tomography and Spectroscopy of Tissue XIII, 108741S (2019/03/01).

O. Tong, A. Chamson-Reig, L. Yip, M. Brackstone, M. Diop, J. JL Carson, " Non-contact imaging of breast surface for breast surgical planning", Proc. SPIE 10856, Diseases in the Breast and Reproductive System V, 108560F (2019/02/26).

R. McManus, E. Froats, K. St Lawrence, S. Van Uum, M. Diop, " Dynamic Relationship between Cerebral Blood Flow and Symptoms of Hypoglycemia", Canadian Journal of Diabetes 42(5), S12 (2018/10/01).

A. Rajaram, K. St Lawrence, M. Diop, "Development of a hybrid broadband NIRS/diffusion correlation spectroscopy system to monitor preterm brain injury", Proc. SPIE 10054, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV, 100540T (2017/04/19).

P. Omidi, M. Diop, J. Carson, M. Nasiriavanaki, "Improvement of resolution in full-view linear-array photoacoustic computed tomography using a novel adaptive weighting method", Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017; 100643H (2017).

P. McLachlan, J. Kishimoto, S. de Ribeaupierre, D. S. C. Lee, M. Diop, K. St Lawrence, "Development of a NIRS method to quantify cerebral perfusion and oxidative metabolism in preterm infants with post-hemorrhagic ventricle dilation", Proc. SPIE 10054, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV, 100540S (2017/04/19).

A. Abdalmalak, D. Milej, M. Diop, L. Naci, A. M. Owen, K. St Lawrence, "Assessing the feasibility of time-resolved fNIRS to detect brain activity during motor imagery", Proc. SPIE 9690, 969002 (2016).

S. Ioussoufovitch, L. B. Morrison, T.-Y. Lee, K. St Lawrence and M. Diop, "Quantification of joint inflammation in rheumatoid arthritis by time-resolved diffuse optical spectroscopy and tracer kinetic modeling", Proc. SPIE 9319, 93191D (2015).

K. Verdecchia, M. Diop, A. Lee, K. St Lawrence, "Characterization of a hybrid diffuse correlation spectroscopy and time-resolved near-infrared spectroscopy system for real-time monitoring of cerebral blood flow and oxygenation", Proc. SPIE 9313, 931310 (2015).

K. Verdecchia, M. Diop, K. St Lawrence, "Investigation of the best model to characterize diffuse correlation spectroscopy measurements acquired directly on the brain", Proc. SPIE 9333, 93330E (2015).

M. Diop and K. St Lawrence, "Boundary conditions independent diffuse correlation spectroscopy", Proc. SPIE 9319, 931917 (2015).

J. Kishimoto, M. Diop, P. McLachlan, S. de Ribaupierre, D.S.C. Lee, K. St Lawrence, "Evidence of ventricular contamination of the optical signal in preterm neonates with post hemorrhagic ventricle dilation", Proc. SPIE 9319, 931908 (2015).

K. M. Tichauer, M. Diop, J. T. Elliott, K. S. Samkoe, T. Hasan, K. St Lawrence, B. W Pogue, "Dual-tracer receptor concentration imaging using tracers with different tissue delivery kinetics", Proc. SPIE 8956, 895607-7 (2014).

J. T. Elliott, M. Diop, L. B. Morrison, T.-Y. Lee, K. St Lawrence, "Reconstruction of cerebral hemodynamics with dynamic contrast-enhanced time-resolved near-infrared measurements before and during ischemia", Proc. SPIE 8578, 85780A-7 (2013).

E. Wright, K. St. Lawrence, M. Diop, "Conversion of a low cost off-the-shelf spectrometer into a suitable instrument for deep tissue spectroscopy", Proc. SPIE 8573, 85730V (2013).

H. Z. Yeganeh, V. Toronov, M. Diop, J. T. Elliott, K. St Lawrence, T.-Y. Lee, “Continuous wave broadband analysis of tissues", Proc. SPIE 8578, 85781C-7 (2013).

M. Diop, K. St Lawrence, "Deconvolution improves the accuracy and depth sensitivity of time-resolved measurements", Proc. SPIE 8578, 85782E-1 (2013).

K. Verdecchia, J. Elliott, M. Diop, L. Hoffman, T.-Y. Lee, K. St Lawrence, "Assessing tumor physiology by dynamic contrast-enhanced near-infrared spectroscopy", Proc. SPIE 8578, 857823-9 (2013).

M. F. Bakhsheshi, J. Hadway, L. B. Morrison, M. Diop, K. St Lawrence, T.-Y. Lee, "Effects of combined xenon and hypothermia on cerebral blood flow and oxygen consumption in newborn piglets measured with a time-resolved near-infrared technique", Proc. SPIE 8579, 85790S (2013).

M. F. Bakhsheshi, M. Diop, K. St Lawrence, T.-Y. Lee, "Quantitative measurement of cerebral blood flow during hypothermia with a time-resolved near-infrared technique", Proc. SPIE 8207, 82074R (2012).

M. Diop, T.-Y. Lee, K. St Lawrence, "Continuous monitoring of absolute cerebral blood flow by combining diffuse correlation spectroscopy and time-resolved near-infrared technology", Proc. SPIE 7896, 78960F (2011).

J. T. Elliott, M. Diop, K. M. Tichauer, T.-Y. Lee, K. St Lawrence, "Monte Carlo based modeling of indocyanine green bolus tracking in the adult human head", Proc. SPIE 7896, 78960E (2011).

J. T. Elliott, K. M. Tichauer, M. Diop, K. St Lawrence, "Fast Monte Carlo fitting of two-layered tissue structures for short source-detector distances", Proc. SPIE 7896, 789611 (2011).

M. Diop, K. M. Tichauer, J. Elliott, T.-Y. Lee, K. St Lawrence, "Time-resolved near-infrared technique for bedside monitoring of absolute cerebral blood flow", Proc. of SPIE, 7555, 75550Z (2010).

A. Rajaram, L. C. M. Yip, M. Kewin, L. B. Morrison, M. Diop, and K. St Lawrence, "Development of a neonatal neuromonitor for concurrent measurements of cytochrome c oxidase and CMRO2", Journal of Cerebral Blood Flow & Metabolism, vol. 39, 183-183 (2019/7/1).

D. Milej, L. He, A. Abdalmalak, W. B. Baker, U. C. Anazodo, M. Diop, J. A. Detre, W. A. Kofke, A. G. Yodh, and K. St Lawrence, "Validation of an optical method for measuring cerebral blood flow in adults", Journal of Cerebral Blood Flow & Metabolism, vol. 39, 486-487 (2019/7/1).

H. Abdallah, S. Ioussoufovitch, E. Wright, L. B. Morrison, L. Desjardins, J. A. Hadway, K. St Lawrence, T.-Y. Lee, F. Beier, and M. Diop, “Longitudinal assessment of disease activity in a rat model of rheumatoidarthritis by monitoring joint blood flow with Computed Tomography perfusion”, Canadian Bone & Joint Conference, London, Canada; Conference Date: 2018/6.

S. Ioussoufovitch, L. B. Morrison, St Lawrence, T.-Y. Lee, and M. Diop, “Assessing Early Treatment Response in an Animal Model of RheumatoidArthritis by Measuring Joint Blood Flow”, Canadian Bone & Joint Conference, London, Canada; Conference Date: 2018/6.

D. Cohen, J. Tse, D. Holdsworth, and M. Diop, “In Silico Investigation ofNear-Infrared Photon Propagation in Bones”, Canadian Bone & Joint Conference, London, Canada; Conference Date: 2018/6.

S. Ioussoufovitch, L. Morrison, L. Desjardins, J. Hadway, K. St. Lawrence, T.-Y. Lee, F. Beier, M. Diop, "Monitoring Joint Blood Flow with DCE TR-NIRS to Assess Treatment Response in Rheumatoid Arthritis", Paper# JW3A.8, OSA Biophotonics Congress; Biomedical Optics, Hollywood, Florida, USA, April 03 – 06, 2018. Won the best poster prize of the conference.

A. Abdalmalak, D. Milej, M. Diop, A. M. Owen, K. St Lawrence, “Towards a robust brain-computer interface based on motor imagery for communicating with patients with brain injuries”, fNIRS 2018, paper#70, Tokyo, Japan, 2018.

D. Milej, A. Abdalmalak, M. Khalid, M. Shahid, A. Rajaram, M. Kewin, M. Diop, K. St Lawrence, “Assessing Extracerebral Signal Contamination in NIRS and DCS”, fNIRS 2018, paper#71, Tokyo, Japan, 2018.

A. Abdalmalak, D. Milej, D. Cohen, T. Ssali, M. Diop, A. M. Owen, and K. St Lawrence, “Are partial volume errors the cause of inverse oxygenation during fNIRS studies of motor-imagery?”, fNIRS 2018, paper#275, Tokyo, Japan, 2018.

A. Rajaram, G. Bale, M. D. Kewin, I. Tachtsidis, K. St. Lawrence, M. Diop, "Hybrid Broadband NIRS/Diffuse Correlation Spectroscopy System for Simultaneous Monitoring of Cerebral Perfusion and Cytochrome C Oxidase", Paper# JW3A.50, OSA Biophotonics Congress; Biomedical Optics, Hollywood, Florida, USA, April 03 – 06, 2018.

W. Baker, A. B. Parthasarathy, L. He, V. C. Kavuri, M. Diop, D. F. Milej, D. R. Busch, K. P. Gannon, M. T. Mullen, J. A. Detre, D. Licht, K. St. Lawrence, R. Balu, W. A. Kofke, A. G. Yodh, "Noninvasive Optical Monitoring of Cerebral Blood Flow, Critical Closing Pressure, and Arteriole Compliance in Adult Human Subjects" Paper#OF4D.1, OSA Biophotonics Congress; Biomedical Optics, Hollywood, Florida, USA, April 03 – 06, 2018.

D. F. Milej, L. He, A. Abdalmalak, W. Baker, U. C. Anazodo, S. Dolui, V. C. Kavuri, M. Diop, W. Pavlosky, R. Balu, J. A. Detre, A. Kofke, A. G. Yodh, K. St. Lawrence, "Quantification of Cerebral Blood Flow in Adults by Dynamic Contrast-Enhanced NIRS: Validation against MRI", Paper#BF2C.2, OSA Biophotonics Congress; Biomedical Optics, Hollywood, Florida, USA, April 03 – 06, 2018.

M. D. Kewin, D. F. Milej, A. Abdalmalak, A. Rajaram, M. Diop, S. de Ribaupierre, K. St. Lawrence, "Validation of a Hyperspectral NIRS Method for Measuring Oxygen Saturation by Comparison to Time-Resolved NIRS", Paper# OW4C.4, OSA Biophotonics Congress; Biomedical Optics, Hollywood, Florida, USA, April 03 – 06, 2018.

M. Khalid, D. F. Milej, A. Rajaram, A. Abdalmalak, M. Diop, K. St Lawrence, "Self-Calibrated DCS for Monitoring Absolute Cerebral Blood Flow", Paper# JTu3A.63, OSA Biophotonics Congress; Biomedical Optics, Hollywood, Florida, USA, April 03 – 06, 2018.

L. He, W. Baker, D. F. Milej, V. C. Kavuri, D. R. Busch, M. Diop, K. St Lawrence, R. Balu, A. Kofke, A. G. Yodh, "Noninvasive Continuous Optical Monitoring of Absolute Cerebral Blood Flow in Adult Human Subjects", Paper# JTu3A.54, OSA Biophotonics Congress; Biomedical Optics, Hollywood, Florida, USA, April 03 – 06, 2018.

S. Ioussoufovitch, L. B. Morrison, K. St Lawrence, T.-Y. Lee, M. Diop, "Measuring Joint Blood Flow with DCE-NIRS: Application to Rheumatoid Arthritis Treatment Monitoring", Imaging Network Ontario, Toronto, ON, Canada, March 28 – 29, 1018.

D. Milej, L. He, A. Abdalmalak, W. B. Baker, S. Dolui, V. C. Kavuri, U. C. Anazodo, M. Diop, W. Pavlosky, R. Balu, J. A. Detre, O. Amendolia, F. Quattrone, W. A. Kofke, A. G. Yodh, K. St. Lawrence, "Non-invasive Optical Quantification of Absolute Cerebral Blood Flow in Adults: Validation against MRI", ARS, AUA and SOCCA 2018 Annual Meetings, Hyatt Regency Chicago, Illinois, USA (2018) (Top 30 submissions).

A. Abdalmalak, D. Milej, L. Norton, D. B. Debicki, T. Gofton, M. Diop, A. M. Owen, K. St. Lawrence, "Communicating with a locked-in patient at the bedside using fNIRS", Traumatic Brain Injury and Concussion, Baycrest's Rotman Research Institute, Toronto, Ontario, Canada (2018).

A. Rajaram, G. Bale, M. Kewin, I. Tachtsidis, K. St. Lawrence, M. Diop, "A novel hybrid broadband near-infrared/diffuse correlation spectroscopy neuromonitor for simultaneous and real-time quantification of cerebral saturation, perfusion, and metabolism at the bedside", Mexican Symposium on Neuroimaging (Oral), Puebla, Mexico, October 20 – 21, 2017.

A. Abdalmalak, D. Milej, L. Norton, D. Debicki, T. Gofton, M. Diop, A. M. Owen, K. St. Lawrence, " Canada, Single-session communication with a locked-in patient", Mexican Symposium on Neuroimaging (Oral), Puebla, Mexico, October 20 – 21, 2017.

A. Rajaram, G. Bale, M. Kewin, I. Tachtsidis, K. St. Lawrence, M Diop, "A novel bedside optical neuromonitor for real-time measurements of cerebral perfusion/metabolism", International Society on Oxygen Transport to Tissue, Halle, Germany, August, 2017.

A. Rajaram, G. Bale, M. Kewin, I. Tachtsidis, K. St. Lawrence, M Diop, "Development of a hybrid broadband NIRS/diffuse correlation spectroscopy system for simultaneous monitoring of cytochrome c oxidase and cerebral perfusion" Functional Near-infrared Spectroscopy (fNIRS-UK), London, UK, August 2017.

A. Rajaram, G. Bale, M. Kewin, I. Tachtsidis, K. St. Lawrence, M Diop, "A bedside optical neuromonitor for real-time monitoring of cerebral perfusion/oxidative metabolism Brain" Monitoring and Neuroprotection in the Newborn (won best poster of the conference), Killarney, Ireland, August 2017. Won the best poster prize of the conference.

A. Rajaram, K. St Lawrence, and M. Diop, "Development of a hybrid broadband NIRS/diffusion correlation spectroscopy system for real-time monitoring of cerebral perfusion and oxygenation in preterm brain injury", Paper#10054-28, SPIE-BiOS - Near Infrared Spectroscopy and Imaging Applications, San Francisco, CA, USA, Jan. 30 2017.

A. Abdalmalak, D. Milej, M. Diop, M. Shokouhi, A. M. Owen, K. St. Lawrence, "Bridging the gap between thoughts and actions: A functional near-infrared spectroscopy study", Imaging Network Ontario, London, Ontario, Canada, 2017 (Talk).

G. Bale, A. Rajaram, M. Kewin, M. Diop, K. St. Lawrence, I. Tachtsidis, "Broadband NIRS cerebral cytochrome-c-oxidase response to anoxia before and after neonatal hypoxic-ischemic injury", Advances in Exp. Med. Biol., Int. Society on Oxygen Transport to Tissue, Halle, Germany, July, 2017.

P. McLachlan, J. Kishimoto, S. de Ribeaupierre, D.S. C. Lee, M. Diop, K. St Lawrence, "Development of a NIRS method to quantify cerebral perfusion and oxidative metabolism in preterm neonates with post hemorrhagic ventricle dilation", Paper#10054-27, SPIE-BiOS - Near Infrared Spectroscopy and Imaging Applications, San Francisco, CA, USA, Jan. 30 2017.

A. Rajaram, L. B. Morrison, K. St Lawrence, T.-Y. Lee, and M. Diop, “Monitoring vascular markers of joint inflammation in a rabbit model of rheumatoid arthritis with time-resolved near-infrared spectroscopy”, 2016 Canadian Bone and Joint Conference, London, Ontario, Canada (Top 20 abstracts; selected for Oral Podium Presentation).

K. Verdecchia, A. Lee, M. Diop, L.B. Morrison, T-Y. Lee, K. St. Lawrence, “Assessing cerebral blood flow changes in adults by a multi-layered diffuse correlation spectroscopy technique” London Health Research Day, London, Ontario, Canada, March 29 2016.

D. Milej, A. Abdalmalak, H. Ahmed, M. Diop, T.-Y. Lee, K. St. Lawrence, “Quantification of blood–brain barrier permeability by time-resolved NIRS”, paper# PTu3A.2, OSA- Biomedical Optics Congress, Hollywood, Florida, April 26, 2016.

J. Kishimoto, S. de Ribaupierre, J.T. Elliot, D.S.C. Lee, M. Diop, K. St. Lawrence, “Preterm neonates with post hemorrhagic ventricle dilation show improvements in cerebral perfusion after ventricle tap: a near infrared spectroscopy study”, London Health Research Day, London, Ontario, Canada, March 29 2016.

A. Rajaram, L. B. Morrison, K. St Lawrence, T.-Y. Lee, M. Diop, “Monitoring vascular markers of joint inflammation in a rabbit model of rheumatoid arthritis with near-infrared spectroscopy”, 2016, London Health Research Day, London, Ontario, Canada, March 29 2016 (Top 30 out of 400 abstracts; selected for Oral Podium Presentation).

D. Milej, A. Abdalmalak, H. Ahmed, M. Diop, T. Y. Lee, Keith St. Lawrence “Assessment of blood–brain barrier permeability using time-resolved optical technique”, 2016, London Health Research Day, London, Ontario, Canada, March 29 2016.

A. Abdalmalak, D. Milej, M. Diop, Lorina Naci, A. Owen, K. St. Lawrence, “Assessing the feasibility of time-resolved fNIRS to detect brain activity during motor imagery”, 2016, London Health Research Day, London, Ontario, Canada (Top 100 out of 400 abstracts).

A. Abdalmalak, D. Milej, M. Diop, M. Shokouhi, L. Naci, A. M. Owen, K. St. Lawrence "Feasibility of fNIRS as a Brain Computer Interface for Studies of Disorders of Consciousness", fNIRS 2016, Paris, France, 2016 (Talk).

D. Milej, A. Abdalmalak, M. Diop, A. Liebert and K. St Lawrence, "A time-resolved subtraction method for evaluating the optical properties of layered turbid media", Paper #9706-41, SPIE BiOS - Optical Interactions with Tissue and Cells XXVII, San Francisco, Feb. 16, 2016.

D. Milej, A. Abdalamalak, M. Diop, K. St. Lawrence "A Subtraction-Based Approach for Enhancing the Sensitivity of Time-Resolved fNIRS", fNIRS 2016, Paris, France, 2016 (Poster).

A. Rajarama, L. B. Morrison, K. St Lawrence, T.-Y. Lee, M. Diop, “Monitoring vascular markers of joint inflammation in a rabbit model of rheumatoid arthritis with time-resolved near-infrared spectroscopy”, OSA- Biomedical Optics Congress, Hollywood, Florida, April 25-28, 2016.

A. Abdalmalak, D. Milej, M. Diop, L. Naci, A. M. Owen, and K. St. Lawrence, "Assessing the feasibility of time-resolved fNIRS to detect brain activity during motor imagery", Paper #9690-1 SPIE BiOS - Clinical and Translational Neurophotonics, San Francisco, CA, Feb. 13, 2016.

K. Verdecchia, M. Diop, L.B. Morrison, T-Y. Lee, K. St. Lawrence, “Application of a Three-Layer Model to Multi-Distance Diffuse Correlation Spectroscopy: Validation Experiments in Pigs”, OSA- Biomedical Optics Congress, Hollywood, Florida, April 25-28, 2016.

A. Abdalmalak, D. Milej, M. Diop, L. Naci, A. Owen, K. St. Lawrence. “Assessing the feasibility of time-resolved fNIRS to detect brain activity during motor imagery”, 2015, Brain and Mind Symposium (BMIS), Western University, London, Ontario, Canada

M. Diop, J. Kishimoto, V. Toronov, D. S. C. Lee, K St Lawrence, "Using a hybrid optical system to detect the uncoupling of cerebral blood flow and cerebral oxidative metabolism in preterm infants undergoing treatment for patent ductus arteriosus", BRAIN-0827, XXVIIth International Symposium on Cerebral Blood Flow, Metabolism and Function, Vancouver, Canada, June 27-30, 2015.

J. Kishimoto, K. St Lawrence, M. Diop, V.K.M. Han, D.S.C. Lee, S. de Ribaupierre, "Limitations of Cerebral Monitoring with Near Infrared Spectroscopy in Neonates with Post Hemorrhagic Ventricular Dilatation", abstract #751592, Pediatric Academic Society, San Diego, CA, April 25-28 2015.

P. McLachlan, J. Kishimoto, K. St Lawrence, M. Diop, V.K.M. Han, D.S.C. Lee, S. de Ribaupierre, "Pitfalls of Cerebral Oxygenation Monitoring in the Presence of Ventricular Dilatation", abstract #755780, Pediatric Academic Society, San Diego, CA, April 25-28 2015.

J. Kishimoto, M. Diop, K. St Lawrence, V.K.M. Han, D.S.C. Lee, "Validation of a Non-Invasive Optical Method, Diffuse Correlation Spectroscopy (DCS), for Measuring Cerebral Blood Flow in Preterm Neonates with PDA undergoing Indomethacin Treatment", abstract #755886, Pediatric Academic Society, San Diego, CA, April 25-28 2015.

J. Kishimoto, J. T. Elliott, P. McLachlan, M. Diop, S. de Ribaupierre, D. S. Lee, and K. St. Lawrence, " Monitoring Cerebral Blood Flow in Preterm Infants with Post-Hemorrhagic Hydrocephalus", Biomedical Optics, Paper# BS3A.6, OSA Optics and Photonics Congress, Miami, Florida, USA, April 26-30, 2014.

K. St. Lawrence, A. Lee, K. Verdecchia, J. Elliott, M. Diop, "Assessing Cerebral Hemodynamics by Dynamic Contrast-Enhanced Near-Infrared Spectroscopy", fNIRS Conference, Montreal, Quebec, Canada, October 10-12, 2014.

M. Diop, J. Kishimoto, D.S. Lee, T.-Y. Lee, K. St. Lawrence, "Cerebral Blood Flow Monitoring in Preterm Infants by Diffuse Correlation Spectroscopy", Biomedical Optics Paper# BS3A.33, OSA Optics and Photonics Congress, Miami, Florida, USA, April 26-30, 2014.

K. Verdecchia, M. Diop, T-Y. Lee, K. St. Lawrence, "Multi-Distance Depth-Resolved Diffuse Correlation Spectroscopy", Biomedical Optics Paper# BM3A.13, OSA Optics and Photonics Congress, Miami, Florida, USA, April 26-30, 2014.

K. Verdecchia, M. Diop, T-Y. Lee, K. St. Lawrence, "Investigating Contamination from the Extracerebral Layer in Cerebral Blood Flow Measured by a Multi-Distance Optical Technique", London Health Research Day, London, Canada, March 18, 2014.

M. Diop, E. Wright, and K. St. Lawrence, "Conversion of a low cost off-the-shelf spectrometer into a broadband continuous-wave near-infrared spectrometer for deep tissue spectroscopy", Paper 8573-29, SPIE-BiOS, San Francisco, California, Feb. 2-7, 2013.

J. T. Elliott, M. Diop, L. B. Morrison, T.-Y. Lee, and K. St. Lawrence, "Dynamic contrast enhanced time-resolved near-infrared measurement of cerebral hemodynamics before and during ischemia", Paper 8578-10, SPIE-BiOS, San Francisco, California, Feb. 2-7, 2013.

K. Verdecchia, J. T. Elliot, M. Diop, L. Hoffman, T.-Y. Lee, and K. St. Lawrence, "Assessment of tumour physiology by dynamic contrast-enhanced near-infrared spectroscopy", Paper 8578-76, SPIE-BiOS, San Francisco, California, Feb. 2-7, 2013.

M. Diop and K. St. Lawrence, "Deconvolution improves the depth sensitivity of time-resolved techniques", Paper 8578-87, SPIE-BiOS, San Francisco, California, Feb. 2-7, 2013.

M. F. Bakhsheshi, J. Hadway, M. Diop, K. St. Lawrence, and T.-Y. Lee, "Effect of xenon/hypothermia on cerebral blood flow and oxygen consumption in newborn piglets with a time-resolved near-infrared technique", Paper 8579-26, SPIE-BiOS, San Francisco, California, Feb. 2-7, 2013.

M. Diop and K. St Lawrence, "A deconvolution method for recovering tissue impulse response from time-resolved measurements", Biomedical Optics, Paper# BTu3A.18, OSA Optics and Photonics Congress, Miami, Florida, April-May 2012.

K. Verdecchia, M. Diop, T-Y. Lee, K. St. Lawrence, "Validating Near-Infrared and Diffuse Correlation Spectroscopy to Measure Oxygen Metabolism in Preterm Infants", London Health Research Day, London, Canada, March 20, 2012.

K. Verdecchia, M. Diop, T.-Y. Lee and K. St Lawrence, "Quantification of Cerebral Blood Flow and Oxygen Metabolism by Combining Time-Resolved Near-Infrared Spectroscopy and Diffuse Correlation Spectroscopy", Biomedical Optics, Paper# BSu2A.3, OSA Optics and Photonics Congress, Miami, Florida, April-May 2012.

J. T. Elliott, M. Diop, T.-Y. Lee, K. St Lawrence, "Cerebral blood flow quantification during ischemia using a multi-distance moments-based time-resolved technique”, Biomedical Optics, Paper# BTu3A.53, OSA Optics and Photonics Congress, Miami, Florida, April-May 2012.

H. Z. Yeganeh, V. Toronov, J. T. Elliott, M. Diop, T.-Y. Lee and K. St Lawrence, "Quantitative measurement of Cerebral Blood Flow, using broad band, continuous wave NIRS", Biomedical Optics, Paper# JM3A.3, OSA Optics and Photonics Congress, Miami, Florida, April-May 2012.

M. Diop, T.-Y. Lee, and K. St Lawrence, "Time-resolved near-infrared and diffuse correlation spectroscopy for continuous measurement of absolute cerebral blood flow", BRAIN 2011, XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function and the Xth International Conference on Quantification of Brain Function with PET, May 2011, Barcelona, Spain.

J. Elliott, M. Diop, L. Morrison, J. Hadway, T.-Y. Lee, K. St Lawrence, "Quantitative measurement of cerebral blood flow in an adult porcine model of ischemia using a time-resolved near-infrared technique", BRAIN 2011, XXVth International Symposium on Cerebral Blood Flow, Metabolism and Function, May 2011, Barcelona, Spain.

K. Verdecchia, M. Diop, K. St. Lawrence, "Assessing the Accuracy of a Novel Optical Technique for Bedside Monitoring of Cerebral Blood Flow", Lawson Health Research Day, London, Canada, March 22, 2011.

M. Diop, T.-Y. Lee, and K. St Lawrence, "Continuous monitoring of absolute cerebral blood flow by combining diffuse correlation spectroscopy with time-resolved near-infrared technology", SPIE Photonics West, Optical Tomography and Spectroscopy of Tissue IX, January 2011, San Fransisco, CA.

J. Elliott, K. Tichauer, M. Diop, and K. St Lawrence, "Fast Monte Carlo Fitting of Two Layered Tissue Structures for Short Source-Detector Distances", SPIE Photonics West, Optical Tomography and Spectroscopy of Tissue IX, January 2011, San Fransisco, CA.

J. Elliott, M. Diop, K. Tichauer, T.-Y. Lee, and K. St Lawrence, "Monte Carlo based modeling of indocyanine green bolus tracking in the adult human head", SPIE Photonics West, Optical Tomography and Spectroscopy of Tissue IX, January 2011, San Fransisco, CA.

M. Diop, K. Tichauer, M. Migueis, T.-Y. Lee, and K. S. Lawrence, "Time-Resolved Near-Infrared Technique for Quantitative Measurements of Cerebral Blood Flow", in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2010), paper BSuD79.

J. Elliott, M. Diop, T. Lee, K. St Lawrence, and K. Tichauer, "Fast Monte Carlo Simulations for Quantifying Optical Properties from Short Source-Detector Separation Geometries", in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2010), paper BSuD42.

J. Elliott, M. Diop, K. Tichauer, T.-Y. Lee, and K. St Lawrence, "Quantification of Cerebral Blood Flow in the Adult Using Near-Infrared Spectroscopy Assisted by Subject-Individualized Monte Carlo Modeling", in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2010), paper #BWA1.

M. Diop, J. Elliott, K. Tichauer, T.-Y. Lee, and K. St Lawrence, "Near-Infrared techniques for bedside measurements of absolute cerebral blood flow", LAM 9, International Conference on Optics and Lasers in Science and Technology for Sustainable Development, Dakar, Senegal, January 2010.

K. Tichauer, M. Diop, K. St Lawrence, and T.-Y. Lee, "A depth-resolved fluorescence lifetime imaging technique for small animals", World Molecular Imaging Conference, Montreal, Quebec, September 2009.

J. Elliot, M. Diop, K. Tichauer, T.-Y. Lee, and K. St Lawrence, "Measurement of Cerebral Blood Flow in the Adult Pig by Depth-Resolved Broadband Near-Infrared Spectroscopy", Brain ‘09 (24rd Int. Symposium on Cerebral Blood Flow, Metabolism, & Function), Chicago, Il, July 2009.

M. Diop, J. Elliott, K. Tichauer, T.-Y. Lee, and K. St Lawrence, "A Broadband Multi-Channel NIRS System for Measuring Focal Ischemic Brain Injury in Newborns", Brain ‘09 (24rd Int. Symposium on Cerebral Blood Flow, Metabolism, & Function), Chicago, Il, July 2009.

M. Diop, J. Elliott, K. Tichauer, L. Keenliside, T. Lee, and K. St Lawrence, "Development of a Broadband Multi-Detector NIRS System for Measuring Regional Cerebral Blood Flow," in Biomedical Optics, OSA Technical Digest (Optical Society of America, 2008), paper BSuE60.