About Us
Our Research Goals
The Parsyan Cancer Research Lab is focussed on understanding how triple negative breast cancer (TNBC) and its surrounding cells change and interact with each other during the disease progression and development of resistance to chemotherapy. These are the major roadblocks in developing more effective treatments. Discovering new molecules, or biomarkers, that are related to TNBC metastases, and its drug resistance is the overarching goal of our research.
Our Research Approach
We are located at the Verspeeten Family Cancer Centre in London, ON and part of the Breast Cancer Canada Translational Research Unit. By using patient-derived models and cutting-edge technologies such as spatial omics, organoids and CRISPR-Cas9, we are working hard to discover new indicators related to TNBC metastases (biomarkers), investigate the effects of novel drugs on resistance and sensitivity to current therapeutic agents and increase our understanding of the role of the immune microenvironment.
TNBC is the most aggressive subtype of breast cancer. TNBC cells change their molecules to grow, while cells surrounding cancer also change to fight it better and to not let it spread. On this battlefield, these cancer cells have been winning. We hope to turn the tide and give TNBC patients a fighting chance.
