Grant Funding
Granting agency: Western University
Grant name: IDI Catalyst grant
Proposal Title: Analysing the gut microbiome from immunotherapy responder animals with immunomodulatory properties
Principal Investigator: Dr. Jeremy Burton
Co-applicant: Dr. Saman Maleki
Amount: $24,675 (CDN)
Support period: 2 years (2023-2025)
Granting agency: Lotte & John Hecht Memorial Foundation
Grant name: Hecht Grant
Proposal Title: Comparing the capacity of healthy donor gut microbiome to responder melanoma patients in activating the immune system and sensitizing hard-to-treat tumors to immunotherapy
Principal Investigator: Dr. Saman Maleki
Amount: $481,488 (CDN)
Support period: 3 years (2023-2026)
Granting agency: Western University
Grant name: IDI stream 2
Proposal Title: Interdisciplinary Development Initiative (IDI) grants, Translational Immuno-Oncology Research Group
Principal Investigator: Dr. John Ronald
Co-PI: Dr. Saman Maleki
Amount: $200,000 (CDN)
Support period: 2 years (2022-2024)
Granting agency: London Regional Cancer Program, Department of Oncology, Western University
Grant name: Catalyst grant
Proposal Title: Bacterial-Based Therapy with Akkermansia Muciniphila to Modulate tumor and Gut
Principal Investigator: Dr. Saman Maleki
Co-applicant: Drs. Jeremy Burton, Ting Lee, John Ronald
Amount awarded: $25,000 (CDN)
Support period: 2 years (2022-2024)
Granting agency: Weston Foundation
Grant name: Catalyst grant
Proposal Title: The role of gut microbiome in conferring sensitivity or resistance to systemic therapy in pancreatic cancer
Principal Investigator: Dr. Saman Maleki
Amount awarded: $450,000 (CDN)
Support period: 3 years (2021-2024)
Granting agency: London Regional Cancer Program, Department of Oncology, Western University
Grant name: Catalyst grants
Proposal Title: Evaluation of gastrointestinal microbiota in prostate cancer patients treated with androgen axis-targeted therapies
Role: Co-applicant
Principal Investigator: Dr. Ricardo Fernandes (Western University)
Amount awarded: $25,000
Support period: 2 years (2021-2023)
Granting agency: Division of Medical Oncology at London Regional Cancer Program
Grant name: MORF
Proposal Title: Association between androgen receptor axis-targeted therapies and gastrointestinal microbiota in patients with prostate cancer
Role: Co-applicant
Principal Investigator: Dr. Ricardo Fernandes (Western University)
Amount awarded: $21,400
Support period: 2 years (2021-2023)
Granting agency Division of Medical Oncology at London Regional Cancer Program Grant name: MORF
Proposal Title: Association between chemotherapy response and gut microbiome in patients with pancreatic cancer
Role: Co-applicant
Principal Investigator: Dr. John Lenehan (Western University)
Amount awarded: $30,000 + 30,000 matching funds awarded to us from The Baker Centre for Pancreatic Cancer
Support period: 2 years (2021-2023)
Granting agency: Canadian Cancer Society
Grant name: Impact Grant Competition
Proposal Title: Fecal microbial transplantation to increase immunotherapy activity in melanoma and non-small cell lung cancer
Role: Co-PI
Principal Investigator: Dr. Bertrand Routy (University of Montreal)
Total amount asked for: $1,489,100(CDN)
Support period: 5 years (2020-2025)
Granting agency: London Regional Cancer Program, Department of Oncology, Western University
Grant name: Catalyst Grants, Keith's Samitt Translational Research Grant
Proposal Title: The role of IL12 and IL27 on inducing CD39 expression on tumor-specific CD8+ T-cells
Role: PI
Total amount asked for: $23,854 (CDN)
Support period: 2 years (2020-2022)
Granting agency: London Regional Cancer Program, Department of Oncology, Western University
Grant name: Catalyst Grants, Keith's Samitt Translational Research Grant
Proposal Title: Preventing immune-related adverse events in renal cell carcinoma patients treated with combination immunotherapy using fecal microbial transplantation
Role: Co-applicant
Principal Investigator: Dr. Ricardo Fernandes (Western University)
Total amount asked for: $24,195 (CDN)
Support period: 2 years (2020-2022)
Granting agency: Academic Medical Organization of Southwestern Ontario (AMOSO)
Grant name: Opportunities Fund
Proposal Title: Preventing immune-related adverse events in renal cell carcinoma patients treated with combination immunotherapy using fecal microbial transplantation
Role: Co-applicant
Nominated Principal Applicant: Dr. Ricardo Fernandes (Western University)
Total amount asked for: $48,750 (CDN)
Support period: 2 years (2019-2021)
Granting agency: Lotte & John Hecht Memorial Foundation
Grant name: Hecht Grant (2 years)
Proposal Title: Combining Fecal Microbial Transplant (FMT) and anti-PD-1 immunotherapy for the treatment of melanoma patients
Role: Co-PI
Total amount: $100,000 (CDN)
Support period: 2 years (2018-2020)
Granting agency: Canadian Institute of Health Research (CIHR)
Grant name: Project Grant
Proposal Title: Inducing mismatch repair deficiency in cancer cells for therapeutic benefit
Role: Co-PI
Nominated Principal Applicant: Dr. James Koropatnick (Western University)
Total amount: $983,025 (CDN)
Support period: 5 years (2018-2023) extended to 2024 because of COVID19
Granting agency: Division of Medical Oncology at London Regional Cancer Program
Grant name: MORF
Proposal Title: A phase I study of the combination of Pembrolizumab and Microbial Fecal Transplantation (FMT) in melanoma patients
PI: Dr. John Lenehan (Western University)
Role: Co-investigator
Total amount: $24,000 (CDN)
Support period: 05/2018-05/2019
Granting agency: Society for Immunotherapy of Cancer (SITC)
Grant name: SITC Sparkathon Emerging Leaders Igniting Innovation Team Grant
Proposal Title: Mentoring for Early Translational Immuno-Oncology Researchers (METIOR) Incubator
Role: Co-applicant
Total amount: $75,000 (USD)
Support period: 10/2017-10/2018
Granting agency: LHSC London Regional Cancer Program (LRCP)
Grant name: Catalyst Program for Translational Cancer Research
Proposal Title: Evaluating Impact of Preoperative Radiation Dosage and Fractionation on Serial Immune Priming Markers in Breast Cancer
Role: Co-investigator
Nominated Principal Applicant: Dr. Muriel Brackstone (Western University)
Total amount asked for: $29,362 (CDN)
Support Period: 02/2019-02/2021
Granting agency: Lawson Health Research Institute
Grant name: Lawson Internal Research Fund
Proposal Title: Differentiating the role of host IDO from tumor IDO in suppressing antitumor immunity.
PI: Dr. Xiufen Zheng (Western University)
Role: Co-investigator
Total amount: $12,922.50 (CDN)
Support Period: 07/2016-06/2018
