Research

Introduction to Research in the Division of Neuropsychiatry

The Division of Neuropsychiatry was created in 2002 to provide academic leadership in neuroscience research wihtin the Department of Psychiatry.  It provides a home for basic science researchers within the department and facilitates more effective collaboration between imaging researchers at the Robarts Research Institute, the Lawson Health Research Institute and clinical research gropus.  The division also allows the development of advanced training opportunities within the department at resident, fellowship, MSc, PhD and postdoctoral levels through collaboration with the Deartments of Medical Biophysics, Anatomy, and Cell Biology, Psychology and the Neuroscience Graduate Program.  The division contributes to clinical service provision through a consultation role with the Department of Clinical Neurological Sciences and with the Acquired Brain Injury program at Parkwood Hospital.

Publications by Members of the Division of Neuropsychiatry

1. Brand, B.L., McNary, S.W., Myrick, A.C., Loewenstein, R.J., Classen, C.C., Lanius, R.A., Pain, C., & Putnam, F.W. (2012). A longitudinal, naturalistic study of dissociative disorder patient treated with community clinicians. Psychological Trauma: Theory, Research, Practice, and Policy, 5(4), 301-308.  Link to the abstract and full text article here.

2. Brand, B.L., Myrick, A.C., Loewenstein, R.J., Classen, C.C., Lanius, R.A., McNary, S. W., Pain, C., & Putnam, F. W. (2012). A survey of practices and recommended treatment interventions among expert therapists treating patients with dissociative disorder and dissociative disorder not otherwise specified. Psychological Trauma: Theory, Research, Practice, and Policy, 4(5), 490-500.  Link to the abstract and full text article here.

3. Daniels, J.K., Bluhm, R.L., & Lanius, R.A. (2013). Intrinsic network abnormalities in posttraumatic stress disorder: Research directions for the next decade. Psychological Trauma: Theory, Research, Practice, and Policy, 5(2), 142-148.  Link to the abstract and full text article here.

4. Ford, K.A., Theberge, J., Neufeld, R.W., Williamson, P.C., & Osuch, E.A. (2013). Correlation of brain default mode network activation with bipolarity index in youth with mood disorders. Journal of Affective Disorders, June 24 (Epub ahead of print).  Link to the pubmed listing here.

5. Frewen, P.A., Evans, B., Goodman, J., Halliday, A., Boylan, J., Moran, G., Reiss, J.P., Score, A., & Lanius, R.A. (2013). Development of a childhood attachment and relational trauma screen (CARTS): A relational-socioecological framework for surveying attachment security and childhood trauma history. European Journal of Psychotraumatology, 4, (Epub ahead of print).  Link to the pubmed listing here.

6. Frewen, P.A., Lundberg, E., Brimson-Theberge, M., and Theberge, J.  "Neuroimaging self-esteem:  A fMRI Study of Individual Differences in Women."  Social Cognitive and Affective Neuroscience.  2013 Jun;8(5):546-55.  Link to the Pubmed listing here. 

7.  Greening, S.G., Osuch, E., Williamson, P.C., & Mitchell, D.G.V.  "Emotion-related brain activity to conflicting socio-emotional cues in unmedicated depression"  Journal of Affective Disorders.   2013 Sep 25;150(3):1136-41.  Link to the Pubmed listing here.

8.  Greenng, S.G., Osuch, E., Williamson, P.C., & Mitchell, D.G.V.  "The neural correlates of regulating postivei and negative emotions in medication-free major depression".  Social Cognitive and Affective Neuroscience.  (Epub ahead of print).  Link to the Pubmed listing here.

9.  Nazarov, A., McKinnon, M., Frewen, P.A., Parlar, M., Oremus, C. MacQueen, G.,   Lanius, R.A. "Theory of mind performance in women with posttraumatic stress disorder related to childhood abuse".  Acta Psychiatrica Scandinaica.   2014 Mar;129(3):193-201.  Link to the Pubmed listing here.

10.  Osuch, E., Vingilis, E., Ross, E., Forster, C., & Summerhurst, C.  "Cannabis use, addiction risk and functional impairment in youth seeking treatment for primary mood or anxiety concerns".  The International Journal of Adolescent Medicine and Health. 2013: 2013;25(3):309-14.  Link to the Pubmed listing here. 

11.  Ros, T., Theberge, J., Frewen, P.,A., Kluetsch, R., Densmore, M., Calhoun, V.D., & Lanius, R.A. "Mind over chatter:  plastic up-regulation of the fMRI salience network directly after EEG neurofeedback.  Neuroimage.   2013 Jan 15;65:324-35.  Link to the Pubmed listing here.

Grants Currently held by Members of the Division of Neuropsychiatry

1. Anagnostou, E., Arnold, P., Lerch, J., Nicolson, R., Schachar, R., Scherer, S., & Szatmari, P. (Co-Investigators).  Province of Ontario neurodevelopment disorders network.  Ontario Brain Institute. $18,750,000; 2013-2018

2. Cloitre, M., Lanius, R.A. (Principal Investigators), Herman, J., & Kaslow, N, (Co- Investigators).  Implementation of an Evidence Based PTSD Treatment in Public Sector Settings.  National Institutes of Mental Health.  $3,090,352 USD; 2011-2014.

3. Fombonne, E., Bryson, S.E., Burack, J.A., Evans, A.C., Iarocci, G., Mirenda, P., Mottron, L., Roberts, S.W.G., Rouleau, G.A., Scherer, S.W., Smith, I.M., Szatmari, P., Volden, J., Zwaigenbaum, L., Anagnostou, E., Boyle, M.H., Brian, J.A., Couture, M., Drapeau, P., Enns, J.T., Fahnestock, M., Johnson, S.A., Kelley, E.A., Kennedy, T.J., Kingstone, A.F., Mazer, B.D., Moore, C., Muckle, G., Nicholas, B., Nicolson, R., Patterson, A.D., Tanaka, J.W., Vaillancourt, T., & Weksberg, R.  CIHR Training Grant in Autism Research.  Canadian Institute of Health Research. $1,950,000; 2009-2015.

4. Forchuk, C., (Principal Investigator), Rudnick, A., Reiss, J.P., Hoch, J., Petrenko, M., Godin, M., Corring, D., Donnelle, L, Edwards, B., Mitchell, B., Neal, D., Ouseley, S., Vingilis, E., Campbell, R., Norman, R.M.G., & Osuch, E.A.  (Co-Investigators). Mental Health Engagement Network (MHEN) – Connecting Clients with their Health Team.  Canada Health Infoway (75%), TELUS and Lawson Health Research Institute (25%).  $1,797,226; 2011-2014.

5. Frewen, P.A., (Principal Investigator), Lanius, R.A., Neufeld, R.W., & Reiss, J.P. 
(Co-Investigators).  Psychological Assessment of Symptom Causal Relations.  Canadian Institute of Health Research.  $54,258;  2011-2014.

6. Lanius, R.A.  (Principal Investigator).  Intergenerational Transmission of Trauma.  Judith Harris Foundation.  $750,000; 2008-2015.

7. Lanius, R.A. (Principal Investigator), & Van Der Kolk, B.  Functional Neuroanatomy of Bilateral Eye Movement During Trauma Script Imagery.  EMDR Association/Institute/Foundation.  $50,000; 2012-2014.

8.  Menon, R.S., (Principal Investigator), Ansari, D., Chronik, B., Culham, J., Cusack, R., Everling, S., Goodale, M., Han, V., Owen, A., & Williamson, P.C.  Centre for Functional and Metabolic Mapping.  Canada Foundation for Innovation – Leading Edge Fund. $2,494,098; 2013-2018.

9. Mitchell, D.G. (Principal Investigator).  Diverse Effects of Emotionally Salient Stimuli on Brain and Behaviour.  NSERC Discovery Grant.  $165,000; 2013-2018.

10. Mitchell, D.G., & Finger, E. (Co - Principal Investigators).  The Impact of Emotional Mimicry and Oxytocin on Frontotemporal Dementia.  Canadian Institute of Health Research Operating Grant.  $239,408; 2013-2018.

11.  Osuch, E.A.  (Principal Investigator), Theberge, J., Williamson, P.C., & Mitchell, D.G.  Functional Neuroimaging of Intrinsic Hemodynamic Networks in Bipolar Disorder, Unipolar Depressive Disorder, and Health Controls:  Finding a Biomarker for Bipolarity.  Pfizer.  $100,000; 2012-2014.

12. Rajakumar, R.  (Principal Investigator).  Molecular Mechanisms of Spatial Memory.  NSERC.  $25,000; 2013-2017.

13. Theberge, J.  (Principal Investigator).  NeuroPsychiatry Imaging Lab (NeuroPIL) hybrid PET/MRI Infrastructure.  Canada Foundation for Innovation – Leaders Opportunity Fund.  $149,895; 2013-2018.

14. Williamson, P.C.,  (Principal Investigator), Osuch,E.A., Drost, D., Menon, R.S., Theberge, J., Neufeld, R.W., Rajakumar, R., & Pavlosky, W.   Candidate Neuronal Circuits in Schizophrenia.  Canadian Institute for Health Research, Operating Grant.  $739,754; 2012-2018.

Events in the Division of Neuropsychiatry

 For more information about events going on in the department of psychiatry, plesae see the events page. 

Opportunities for Residents and Clerks

There are many opportunities for Residents and Clerks to become involved in research within the department of Neuropsychiary.  Please contact Sheri Lee Bradshaw for more information.