Dr. Cindy Hutnik
Dr. C.M.L. Hutnik BSc, MD, PhD, FRCS(C)
Ivey Eye Institute
St. Joseph's Hospital
268 Grosvenor Street
London, Ontario N6A 4V2
Phone: 519.646.6100 x.66272
Fax: 519.646.6410
Specialty: Glaucoma and Comprehensive Ophthalmology
Clinical Focus: Adult Glaucoma and Cataracts
Residency: Western University
Appointment:
Professor and Chair
Department of Ophthalmology
Schulich School of Medicine & Dentistry
Western University
Ophthalmologist-in-Chief
Ivey Eye Institute
St. Joseph’s Health Center
Chair of the Governing Committee
Academic Medical Organization of Southwestern Ontario
Dr. Hutnik is Professor and Chair in the Department of Ophthalmology at the Schulich School of
Medicine and Dentistry, Western University, and Ophthalmologist-in-Chief at the Ivey Eye Institute
in London, Ontario, Canada. She holds the inaugural Marcel and Louise Brunette Research Chair in
Ophthalmology at Western.
She served as Medical Director of the Ophthalmology Basic Science Laboratory at the Lawson
Health Research Institute in the Center for Clinical Investigation and Therapeutics for 18 years and
Chair of Research in the Department of Ophthalmology for 15 years. She earned her doctoral
degree at the National Research Council followed by undergraduate medical training, both in
Ottawa, Canada. She then obtained her ophthalmology training at the University of Western
Ontario, in London, Canada followed by subspecialty glaucoma training under the mentorship of Dr.
Paul Kaufman at the University of Wisconsin, Madison, USA.
Her leadership roles have included President of the Canadian Glaucoma Society and Chair of the
Governing Committee of the Academic Medical Association of Southwestern Ontario (AMOSO). Her
administrative roles have included Faculty Chair of the Summer Research Training Program at the
University of Western Ontario as well as membership on the Faculty Clinician-Scientist committee,
MD/PhD selection committee, Medical Advisory Committee of the Canadian National Institute for
the Blind Mobile Eye Care Program, councilor and secretary/treasurer of the Canadian Glaucoma
Society and co-chair of the Canadian Glaucoma Clinical Research Council. She is currently the
provincial Academic Representative of the Eye Physician and Surgeons of Ontario (EPSO) as well as
a Board member of the Glaucoma Research Society of Canada.
Her major research interest is focused on the pathophysiology and management of glaucoma. She
has supervised and mentored in focused research activities more than 200 students at all levels of
training ranging from high school to graduate science and medicine. Her work has been presented
and published both nationally and internationally and has been recognized with over 95 awards.
She continues to have keen interest in the development of novel and/or optimization of existing
treatments for patients with glaucoma. Believing strongly in collaborative models of eye care she is
proud to be the co-creator of the London and District Interprofessional Model of Care (LDIM) aimed
at improving access to care for patients with glaucoma.
Publications
Medical Education
Deans, A.M., Basilious, A., Hutnik, C.M.L. Assessing the performance of a novel Bayesian algorithm at point of care for red eye complains. Vision 2022:6;64,Doi.org/10.3390/vision6040064.
Kryshtalskyj, M.T., Dzulynsky, K., Mak, M.Y.K., Hutnik, C.M.L. Research productivity of ophthalmology residents and its relationship to academic career outcomes. Canadian Journal of Ophthalmology 2022; Oct 25:S0008-4182(22)00301-5. Doi:10.1016/j.cjo.2022.09.005. Online ahead of print.
Kryshtalskyj, M.T., Novello, M.J., Malvankar-Mehta, M.S., Nicolela, M., Hutnik C.M.L. Scholarly impact of academic ophthalmologists and vision scientists in Canada. Clinical Ophthalmology 2021;15:4513-4525.
Lim, C. and Hutnik, C.M.L. Soft skill development in Ophthalmology and its importance to aspiring Canadian medical students. UOJM 2018;8(1):17-22.
Clinical Research
Malvankar-Mehta, M.S., Rahaman, M., Suri, A., Hutnik, C.M.L. Evidence of stroke in glaucoma patients: A meta-analysis. Journal of Stroke Medicine 2023:In Press.
Salimi A., Kangee, R., Popovic, M., Hutnik, C.M.L., Ahmed, I. Prophylaxis against intraocular pressure spikes following uncomplicated phacoemulsification: A systematic-review and meta-analysis. Br J Ophthalmol 2023;
Krance, S.H., Hutnik, C.M.L., Fraser, J.A. Superior altitudinal hemi-field visual hallucinations in Charles Bonnet Syndrome. Can J Ophthalmol 2023 Feb 11, doi:10.1016/j.cjo.2023.01.010.
Vinokurtseva, A., Quinn, M.P., Wai, M., Leung, V., Hutnik, C.M.L. Using Consensus-based standards for the selection of health measurement instruments to assess measurement properties of patient reported outcome measures in glaucoma: A systematic review. Clinical and Experimental Ophthalmology 2022:49(8);908-909.
Ho, E., Wang, E., Youn, S., Sivajohan, A., Lane, K., Chun, J., Hutnik, C.M.L. Deep ensemble learning for retinal image classification. Translational Vision Science & Technology 2022:Oct 3;11(10):39. Doi:10.1167/tvst.11.10.39.
Vinokurtseva, A., Fung, M., Li, E., Zhang, R., Armstrong, J.J., Hutnik, C.M.L. Impact of inhaled and intranasal corticosteroids exposure on the risk of ocular hypertension and glaucoma: A systematic review and meta-analysis. Clin Ophthalmol 2022:16;1675-1695.
Hutnik, C.M.L., Kryshtalskyj, M.T., Madjedi, K.M., Crichton, A.C.S. Spot the differences: Challenges in detecting glaucoma in the myopic patient. Canadian Eye Care Today 2022:1(1);20-25.
Yu, B., Cheung, R., Hutnik, C.M.L., Malvankar-Mehta, M.S. Prevalence of obstructive sleep apnea in glaucoma patients: A systematic review and meta-analysis. Journal of Current Glaucoma Practice 2021:15(3);109-116.
Armstrong, J.J., Zhang, R., Fung, M., Zeman-Pocrnich, C., Rotenberg, B., Bauman, G., Gilbert, K., Hutnik, C.M.L. Rapid visual field progression in a patient with glaucoma as the presenting manifestation of sarcoidosis. Am J Ophthalmol Case Rep. 2021:5:23:101132.
Harasymowycz, P., Hutnik, C.M.L., Rouland, J.F., Munoz Negrete, F.J., Economou, M.A., Denis, P., Baudouin, C. Preserved versus preservative-free latanoprost for the treatment of glaucoma and ocular hypertension: A post-hoc pooled analysis. Advances in Therapy 2021:38(6);3019-3031.
Wong, K., Lim, C.W., Malvankar-Mehta, M.L. Hutnik, C.M.L. Effectiveness of topical cycloplegics to treat pain in the setting of anterior segment injury or inflammation: A systematic review and meta-analysis. Canadian Journal of Ophthalmology 2021:56(4);256-267.
Konstas, A.G., Schmetterer, L., Katsanos, A., Hutnik, C.M.L., Hollo, G., Quaranta, L., Teus, M.A., Uusitalo, H., Pfeiffer, N., Katz, L.J. Dorzolamide/timolol fixed combination: Learning from the past and looking toward the future. Adv Ther 2020:doi.org/10.1007/s12325-020-01525-5.
Malvankar-Mehta M.S., Fu, A., Subramaniam, Y., Hutnik, C.M.L. Impact of ophthalmic viscosurgical devices in cataract surgery. Journal of Ophthalmology 2020:ID 7801093, doi.org/10..1155/2020/7801093.
Kansal, V., Armstrong, J.J., Hutnik, C.M.L. Trends in glaucoma filtration Procedures: A retrospective administrative health records analysis over a 13-year period in Canada. Clinical Ophthalmology 2020:14;501-508.
Uruthiramoorthy, L., Hutnik, C.M.L., Speechley, K.N., Malvankar-Mehta, M.S., Lizotte, D.J. Estimating Patient-Reported Outcomes for Glaucoma Management: Cross-sectional study. Journal of Evidence-Based Medicine 2020: DOI: 10.1111/jemb.12369;1-9.
Lim, C., Diaconita, V., Liu, E., Ault, N., Lizotte, D., Nguyen, M., Hutnik, C.M.L. Effect of a 6-week washout period on intraocular pressure following chronic prostaglandin analogue treatment: a randomized controlled trial. Can J Ophthal 2019:55(2);143-151.
Bao, B., Diaconita, V., Hutnik, C.M.L. Tono-pen versus Goldmann applanation tonometry: a comparison of 898 eyes. Ophthalmology Glaucoma 2019:2(6);435-439.
Malvankar-Mehta MS, Feng L, Hutnik CML. North American cost analysis of brand name versus generic drugs for the treatment of glaucoma. ClinicoEconomics and Outcomes Research 2019:11;789-798.
Poitras, V., Wells, C., Hutnik, C.M.L., Klarenback, S., So, H., Smith, A., Herington, E., Brender, N., Wells, C., Ford, C., Severn, M. Optimal use of minimally invasive glaucoma surgery: A health technology Assessment. Free Access Via Internet, Ottawa, ON. Canadian Agency for Drugs and Technologies in Health 2019 Jan.
Filek, R., Hooper, P., Sheidow, T., Gonder, J., Chakrabarti, S., Hutnik, C.M.L. Two-year analysis of changes in the optic nerve and retina following anti-VEGF treatments in diabetic macular edema patients. Clinical Ophthalmology 2019:13;1087-1096.
Kiatos, E., Armstrong, J.J., Tsioris, S.M., Hutnik, C.M.L., Malvankar-Mehta, M.S. Hodge, W.G. Of phaco and pain management: Our review and meta-analysis of intravenous sedation in modern cataract surgery. Ophthalmology Management 2019:23(1);46-54.
Basilious, A., Basilious, A., Mao, A., Hutnik, C.M.L. Trends in low vision care provided by ophthalmologists in Ontario between 2009 to 2015. Can J Ophthal 2019:54(2);229-236.
Armstrong, J.J., Welk, B.K., Reid, J.S., Kansal, V., Hutnik, C.M.L. Secondary surgical intervention after primary glaucoma filtration surgery: An Ontario population-based study. Can J Ophthal 2019:54(2);212-222.
Hutnik, C.M.L., Crichton, A., Ford, B., Nicolela, M., Shuba, L., Birt, C., Sogbesan, E., Damji, K., Dorey, M., Saheb, H., Klar, N., Guo, H, Hodge, W. Selective laser trabeculoplasty versus argon laser trabeculoplasty in glaucoma patients treated previously with 360-degrees selective laser trabeculoplasty: A randomized, single-blind, equivalence clinical trial. Ophthalmology 2019:126(2):223-232.
Diaconita, V., Quinn, M., Jamal, D., Dishan, B., Malvankar-Mehta, M., Hutnik, C.M.L. Washout duration of prostaglandin analogues—A systematic review and meta-analysis. Journal of Ophthalmology 2018:3190684.
Fan, S.K.Y., Stojanovic, D., Malvankar-Mehta, M.S., Hutnik, C.M.L. Antiviral treatment of active herpes zoster ophthalmicus in immunocompetent adults: A systematic review and Canadian cost comparison. Canadian Journal of Ophthalmology 2018:53(2);117-123.
Armstrong, J.J and Hutnik, C.M.L. Comment on Selective Laser Trabeculoplasty, Editor’s Selection, International Glaucoma Review 2018:18-4;52.
Kansal, V., Armstrong, J., Pintwala, R., Hutnik, C.M.L. Optical coherence tomography for glaucoma diagnosis: An evidence based meta-analysis. PLOS ONE 2018:13(1): e0190621.
Hutnik, C.M.L. Efficacy and cost-comparison of Herpes Zoster Ophthalmicus treatment. Expert Comment. Eye Care 2018: www.practiceupdate.com/content/efficacy-and-cost-comparison-of-herpes-zoster-ophthalmicus-treatment/59429/65/5/1.
Basic Science
Teplitsky, J.E., Vinokurtseva, A., Armstrong, J.J., Denstedt, J., Liu, H., Hutnik, C.M.L. Effects of SB-431542 compared to mitomycin C in human Tenon’s capsule fibroblasts. TVST 2023;In Press.
Vinokurtseva, A., Armstrong, J.J., Liu, H., Hutnik, C.M.L. Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon’s capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery. Exp Eye Res 2022:Oct 20:109284.doi:10.1016/j.exer.2022.109284. Online ahead of print.
Vinokurtseva, A., Armstrong, J.J., Liu, H., Kiser, P., Hutnik, C.M.L. Intravitreal injection of COX-2 acetylating immune-resolvents for the treatment of ocular inflammation: In vitro assessment of THP-1-dervied macrophages and in vivo assessment in a rat model of endotoxin-induced uveitis. Clinical and Experimental Ophthalmology 2022:49(8);975.
Vinokurtseva, A., Armstrong, J.J. Li., E., Liu, H., Hutnik, C.M.L. Comparison of acetylsalicylic acid and mitomycin C in Tenon’s capsule fibroblasts: distinct effects on cytokine-induced myofibroblast activity and implications for glaucoma surgery. IOVS 2022:63(7);438.
Armstrong, J.J., Fung, M., Liu, H., Hutnik, C.M.L. Investigating fibroblast-mediated changes to outflow capacity: A novel in vitro model of the subconjunctival outflow tract after glaucoma surgery. Clinical and Experimental Ophthalmology 2022;49(8):909-910.
Petroff, A., Pena Diaz, A., Armstrong, J.J., Gonga-Cave, B.C., Hutnik, C.M.L., O’Gorman, D.O. Understanding inflammation-associated ophthalmic pathologies: a novel 3D co-culture model of monocyte-myofibroblast immunomodulation. Ocular Immunology and Inflammation 2021:14;1-12.
Li, X., Filek, R., Zhu, X., Gao, H., Qiao, L., Liu, H., Xie, L., Wang, Y., Pan, F., Hutnik C.M.L. “Bio-modulation of scarring in glaucoma filtration surgery using a novel application of coated magnesium. Journal of Magnesium Alloys 2021:9(3);883-894.
Vinokurtseva., A., Armstrong, J.J., Liu, H., Kiser, P., Hutnik, C.M.L. Treatment of ocular inflammation: effects of COX-2 acetylating immune-resolvents (CAIRS) in THP-1-derived macrophages and a rat model of endotoxin-induced uveitis. Investigative Ophthalmology and Visual Science 2021:62(8);3452-3452.
Zhang, R., Armstrong, J.J., Hutnik, C.M.L. Development of a thermosensitive hydrogel for sustained drug release and in situ bleb support. Investigative Ophthalmology and Visual Science 2021:62(8);3435-3435.
Fung, M., Armstrong, J.J., Liu, H., Hutnik, C.M.L. Development of a novel bioartificial surgical outflow tract model for rapid screening of anti-fibrotic adjuvants. Investigative Ophthalmology and Visual Science 2021:62(8);3436-3436.
Trelford, C.B., Denstedt, J., Armstrong, J.J., Hutnik, C.M.L. The pro-fibrotic behavior of human Tenon’s capsule fibroblasts in medically treated glaucoma patients. Clinical Ophthalmology 2020:14;1391-1402.
Filek, R., Hooper, P., Sheidow, T., Liu, H., Chakrabarti, S., Hutnik, C.M.L. Safety of anti-VEGF treatments in a diabetic rat model and retinal cell culture. Clinical Ophthalmology 2019:13;1097-1114.
Tellios, N., Feng, M., Chen, N., Liu, H., Tellios, V., Wang, M., Li, X., Chang, C., Hutnik, C.M.L. Mechanical stretch upregulates Connexin43 in human trabecular meshwork cells. Clinical and Experimental Ophthalmology 2019:47(6):787-794. doi: 10.1111.ceo. 13492 [Epub ahead of print].
Armstrong, J.J., Denstedt, J.T., Trelford, C.B., Hutnik, C.M.L. Differential effects of dexamethasone and indomethacin on Tenon’s capsule fibroblasts: implications for glaucoma filtration surgery. Experimental Eye Research 2019; 182:65-73.
Li., X., Xie, L., Pan, F., Wang, Y., Liu, H., Tang, Y., Hutnik, C.M.L. A feasibility study of using biodegradable magnesium alloy in glaucoma drainage devices. International Journal of Ophthalmology 2018;11(1):135-142.
Tellios, V., Liu, H., Tellios, N., Hutnik, C.M.L. Administration of nitric oxide through a novel copper-chitosan delivery system in human corneal and limbal epithelial cellular injury. IOVS 2018; 59:967-977.
