Publications
Periostin modulates collagen and fibronectin synthesis, but not myofibroblast differentiation during gingival healing. Kim SS, Nikoloudaki, GM, Michelsons S, Creber K, Hamilton DW. (In press, Scientific Reports, November 2018)
Matrix composition in 3-D collagenous bioscaffolds modulates the survival and angiogenic phenotype of human chronic wound dermal fibroblasts. Morissette Martin P, Grant A, Hamilton DW, Flynn LE. Acta Biomater. 2018 Oct 29.
Phenytoin activates Smad3 phosphorylation and periostin expression in drug-induced gingival enlargement. Kim SS, Nikoloudaki G, Darling M, Rieder MJ, Hamilton DW. Histol Histopathol, 2018 Jun 19:18015
Periostin as a multifunctional modulator of the wound healing response. Walker JT, McLeod K, Kim S, Conway SJ, Hamilton DW. Cell Tissue Res. 2016 Sep; 365(3):453-65. Review.
Genetic Deletion of Galectin-3 Does Not Impair Full-Thickness Excisional Skin Healing. Walker JT, Elliott CG, Forbes TL, Hamilton DW. J Invest Dermatol. 2016 May; 136(5):1042-50
Nifedipine and phenytoin induce matrix synthesis, but not proliferation, in intact human gingival connective tissue ex vivo. Kim SS, Michelsons S, Creber K, Rieder MJ, Hamilton DW. J Cell Commun Signal. 2015 Aug 23
Regulation of matrix remodelling phenotype in gingival fibroblasts by substratum topography. Kim SS, Wen W, Prowse P, Hamilton DW. J Cell Mol Med. 2015 Jun;19(6):1183-96. Epub 2015 Mar 12. PMID: 25766369
Inflammatory microenvironment and tumor necrosis factor alpha as modulators of periostin and CCN2 expression in human non-healing skin wounds and dermal fibroblasts. Elliott CG, Forbes TL, Leask A, Hamilton DW. Matrix Biol. 2015 Apr;43:71-84. PMID:25779637
S Kim, L Jackson, T Daley, M Darling, M Reider and DW Hamilton. Nifedipine Induces Periostin Expression in Gingival Tissue Through Canonical Transforming Growth Factor Beta Signalling. J Dental Research. 92(11):1022-8, 2013.
Costa DO, Prowse PD, Chrones T, Sims SM, Hamilton DW, Rizkalla AS, Dixon SJ. The differential regulation of osteoblast and osteoclast activity by surface topography of hydroxyapatite coatings. Biomaterials. 34(30):7215-26, 2013.
Chau E, Daley T, Darling MR, Hamilton D. The expression and immunohistochemical localization of periostin in odontogenic tumors of mixed epithelial/mesenchymal origin. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Aug;116(2):214-20.
Prowse PD, Elliott CG, Hutter J, Hamilton DW. Inhibition of Rac and ROCK Signalling Influence Osteoblast Adhesion, Differentiation and Mineralization on Titanium Topographies. PLoS One. 2013;8(3):e58898. doi: 10.1371/journal.pone.0058898. Epub 2013 Mar 7.
Ertorer E, Vasefi F, Keshwah J, Najiminaini M, Halfpap C, Langbein U, Carson JJ, Hamilton DW, Mittler S. Large area periodic, systematically changing, multishape nanostructures by laser interference lithography and cell response to these topographies. J Biomed Opt. 2013 Mar;18(3):035002. doi: 10.1117/1.JBO.18.3.035002. PMID: 23460125.
Ghrebi S, Hamilton DW, Douglas Waterfield J, Brunette DM. The effect of surface topography on cell shape and early ERK1/2 signaling in macrophages; linkage with FAK and Src. J Biomed Mater Res A. 2013 Feb 20. doi: 10.1002/jbm.a.34509. Epub ahead of print
Elliott CG, Kim SS, Hamilton DW. Functional significance of periostin in excisional skin repair: is the devil in the detail? Cell Adh Migr. 2012 Jul-Aug;6(4):319-26. Epub 2012 Jul. PubMed
X. Guo, C.G. Elliott, Z. Li, Y. Xu, D.W. Hamilton, J. Guan. Creating 3D angiogenic growth factor gradients in fibrous constructs to guide fast angiogenesis. Biomacromolecules. 2012 Oct 8;13(10):3262-71. Epub 2012 Sep PubMed
C.G. Elliott, J. Wang, X. Guo, S.W. Xu, M. Eastwood, J. Guan, A. Leask, S.J. Conway, D.W. Hamilton. Periostin modulates myofibroblast differentiation during full-thickness cutaneous wound repair. J Cell Sci. 125(Pt 1):121-32, 2012. Pub Med
C.G. Elliott, D.W. Hamilton. Deconstructing fibrosis research: do pro-fibrotic signals point the way for chronic dermal wound regeneration? J Cell Commun Signal, 2011. PubMed
D.W. Hamilton, C.J. Oates, A. Hasanzadeh, S.M. Mittler. Migration of Periodontal Ligament Fibroblasts on Nanometric Topographical Patterns: Influence of Filopodia and Focal Adhesions on Contact Guidance. PLoS ONE, 5(12):e15129, 2010. PubMed
W. Wen, E. Chau, L. Jackson, T. Daley and D.W. Hamilton. TGF beta 1 and FAK Regulate Periostin Expression in PDLFibroblasts. Journal of Dental Research, 89(12):1439-43, 2010. PubMed
K. Thompson, D.W. Hamilton and A. Leask. ALK5 Inhibition Blocks TGFbeta-induced CCN2 Expression in Gingival Fibroblasts. Journal of Dental Research, 89(12):1450-4, 2010. PubMed
H.M. Zhou, J. Wang, C. Elliott, W. Wen, D.W. Hamilton and S.J. Conway. Spatiotemporal expression of periostin during skin development and incisional wound healing: lessons for human fibrotic scar formation. Journal of Cell Communication and Signaling, 4(2):99-107, 2010. PubMed
SM.Z. Khaled, R.J. Miron, D.W. Hamilton, P.A. Charpentier and A.S. Rizkalla. Reinforcement of Resin Based Cement with Titania Nanotubes. Dental Materials, 262:169-178, 2010. Pub Med
R. Miron, C.J. Oates, A. Molenberg, M. Dard and D. W. Hamilton. The effect of enamel matrix proteins on the spreading, proliferation and differentiation of osteoblasts cultured on titanium surfaces. Biomaterials, 31(3): 449-60, 2010. Pub Med
D.W. Hamiton, C. Oakley, N.A.F. Jaeger and D.M. Brunette. Directional Change Produced by Perpendicularly-Oriented Microgrooves is Microtubule-Dependent for Fibroblasts and Epithelium. Cell Motility and the Cytoskeleton, 66(5):260-71, 2009.
M. Schuler, D.W. Hamilton, T.P. Kunzler, C. M. Sprecher, M. de Wild, D.M. Brunette, M. Textor and S. Tosatti. Response of osteoblasts outgrown from rat calvarial bone chips to non-fouling KRSR and FHRRIKA-peptide rough modified titanium surfaces. In press, Journal of Biomedical Materials Research Part B, Applied Biomaterials, 2009.
L. Jackson-Boeters, W. Wen and D.W. Hamilton. Periostin localizes to cells in normal skin, but is associated with the extracellular matrix during wound repair. Journal of Cell Communication and Signaling, 2009. 3(2):125-133, 2009 PubMed
D.W. Hamilton. Functional Role of Periostin Expression in Development and Wound Repair: Implications for Connective Tissue Disease. Journal of Cellular Communication and Signaling, 2(1-2):9-17, 2008. PubMed
E. Kokubu, D.W. Hamilton, T. Inoue and D.M. Brunette. Modulation of Human Gingival Fibroblast Adhesion, Morphology, tyrosine phosphorylation, and ERK 1/2 localization on Polished, Grooved and SLA Substratum Topographies. Journal of Biomedical Materials Research Part A, 2008.
M. Nematollahi, D.W. Hamilton and D.M. Brunette. Hexagonal Micron Scale Pillars Influence Epithelial Cell Adhesion, Morphology, Migration and Cytoskeletal Organization. Journal of Biomedical Materials Research Part A, 2008.
D.W. Hamilton, B. Chehroudi and D.M. Brunette. Comparative response of epithelial cells and osteoblasts to microfabricated tapered pit topographies in vitro and in vivo. Biomaterials, 28(14):2281-2293, 2007. PubMed
T.M. Maul, D.W. Hamilton, A. Nieponice and D.A Vorp. A novel experimental system for the extended application of cyclic hydrostatic pressure to cell culture. Journal of Biomechanical Engineering, 129(1):110-6, 2007. PubMed
D.W. Hamilton and D.M. Brunette. The effect of substratum topography on osteoblast adhesion mediated signal transduction and phosphorylation. Biomaterials, 28(10): 1806-1809, 2007. PubMed
D.W. Hamilton, K.S. Wong and D. M. Brunette. Microfabricated Discontinuous Edge Surface Topographies Influence Osteoblast Adhesion, Migration, Cytoskeletal Organization, Proliferation and Enhance Matrix and Mineral Deposition in vitro. Calcified Tissue International, 78(5):314-25, 2006. PubMed
M. Schuler, G.Rh. Owen, D.W. Hamilton, M. Wieland, D.M. Brunette, M. Textor and S. Tosatti. Biomimetic Modification of Titanium Dental Implant Model Surfaces Using the RGDSP-Peptide Sequence: A Preliminary Study for a Cell-Selective Surface. Biomaterials, 27(21):4003-4015, 2006. PubMed
D.W. Hamilton, M. Riehle, W. Monaghan, and A.S.G. Curtis. Chondrocyte Aggregation on Micrometric Surface Topography: A time-lapse study. Tissue Engineering, 12(1), p189-199, 2006. PubMed
D.W. Hamilton, S. Ghrebi, H. Kim, B. Chehroudi and D. M. Brunette. Surface Topography and Cell Behaviour. The Encyclopedia of Biomaterials and Biomedical Engineering. Published online 28/11/2005. Editors, Gary Bowlin and Gary Wnek. Marcel Dekker, New York, P1-11.
D.M. Brunette, D.W. Hamilton, B. Chehroudi and J.D. Waterfield. Update on improving the bio-implant interface by controlling cell behaviour using surface topography. International Congress Series, 1284C, p229-238, 2005. LinkedOut
D.W. Hamilton and D.M. Brunette. Gap Guidance of Fibroblasts and Epithelial cells by Discontinuous Surface Topography. Experimental Cell Research, vol 309(2), p429-437, 2005. PubMed
D.W. Hamilton, M. Riehle, R. Rappuoli, W. Monaghan, R. Barbucci and A.S.G. Curtis. The response of primary articular chondrocytes to micrometric topography and sulphated hyaluronic acid based matrices. Cell Biology International, vol 29(8), p605-615, 2005. PubMed
D.W. Hamilton, M. Riehle, W. Monaghan and A.S.G. Curtis. Chondrocyte passage number: Influence on adhesion, migration, cytoskeletal organization and phenotype in response to nano- and micro-metric topography. Cell Biology International, vol 29(6), p408-421, 2005. PubMed
D.W. Hamilton and D.A. Vorp. Tissue Engineering, Blood Vessel. In the Encyclopedia of Biomaterials and Biomedical Engineering. Published online 08/31/04, print, 06/30/2004. Editors, Gary Bowlin and Gary Wnek. Marcel Dekker, New York. p1491-1499.
D.W. Hamilton, T.M. Maul and D.A. Vorp. Characterization of the response of Bone Marrow Derived Progenitor Cells to Cyclic Strain: Implications for Vascular Tissue Engineering Applications. Tissue Engineering, vol 10(3/4), p361-369, 2004. PubMed
M. Riehle, D. Ferris, D. Hamilton and A. Curtis. Cell Behaviour in Tubes. Exp Biol. Online vol 3:2, p1-15, 1998.
