Joseph F. Megyesi, MD, PhD, FRCSC
Professor of Neurosurgery, Western UniversityOffice: London Health Sciences Centre, University Hospital
Phone: 519-663-3565
Secretary: Karen Hailstone
Bio Sketch
Dr. Joseph Megyesi received his MD from Western University in 1985. He then completed a comprehensive surgical internship and a Master's degree in Biochemistry, also at Western University. He did his neurosurgical residency at the University of Alberta in Edmonton, where he also received his PhD degree in Experimental Surgery. As part of his training, Dr. Megyesi completed a fellowship at Harvard University.
Dr. Megyesi joined the Clinical Neurological Sciences Department at Western University in 1998 and specializes in neurosurgical oncology. He is chairman of the Scientific Program Committee at the Canadian Neurological Sciences Federation, sits on the Continuing Professional Development Committee at the Royal College of Physicians and Surgeons of Canada and is past-chairman of the board of the Brain Tumour Foundation of Canada. He is currently Professor in the Division of Neurosurgery at Western University.
Research
Dr. Megyesi's clinical research interests focus on angiogenesis in brain tumors. A tumor's ability to grow is linked to its ability to recruit a supply of new blood vessels. In order to do this, it sends out "signals" to already existing blood vessels to sprout new branches to feed it. This is the process of angiogenesis. His past studies have investigated angiogenic growth factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF).
Dr. Megyesi's research interests also include cerebral vasospasm in the brain. Cerebral vasospasm is delayed-onset, prolonged and pathological cerebral arterial narrowing following aneurysmal subarachnoid hemorrhage (SAH). His past work has looked at the treatment of this disorder using transluminal balloon angioplasty in an animal model.
Medical Interests
Cerebral Vasospasm, HIV Neuropathology, Technical Aspects of Intracranial Surgery, Angiogenisis and Invasion of Brain Tumours, Intratumoral Drug Delivery Systems for Malignant Brain Tumours, Molecular Signatures of Brain Tumours
Honours and Awards
- 2017, Leader of Distinction Award, Brain Tumour Foundation of Canada
- 2017, Ontario Volunteer Service Award, Ontario Mnistry of Citizenship and Immigration
- 2011, Distinguished Reviewer of the Year Award, Canadian Journal of Neurological Sciences
Publications
News
- Life Sciences students shed new light on brain tumours, win research competition - University of Ontairo Institute of Technology
- Simple, cheap drug holds cancer treatment promise - CTV News
- Les Carter's legacy honours doctor's skill - Lonodn Free Press
- Brain tumour fellowship named for Bill Nash - Ingersoll Times
- Dr. Joe's Story - Brain tumour Foundation