$13 million for health research in London

Scientists at The University of Western Ontario and the Lawson Health Research Institute jointly received more than $13-million from the Canadian Institutes of Health Research (CIHR) in support of an array of medical research this week. Western researchers receiving funding include investigators from Schulich Medicine & Dentistry, Robarts Research Institute, Lawson Health Research Institute and the Richard Ivey School of Business.

The announcement included operating funding for a total of 28 London projects ranging from research into osteoarthritis and kidney damage to prenatal health and obesity. London researchers continue to do very well in a highly competitive national funding environment. The funding success rate for applications submitted from London scientists to CIHR was 27% while the national average was 17%.

A list of successful projects is below:

Frank Beier received $713,501 (5 years) for the project, "TGFalpha/EGFR signaling in osteoarthritis"

Nica Borradaile received $91,439 (1 year) for "Roles of elongation factor 1A-1 in apolipoprotein B metabolism and the pathogenesis of nonalcoholic fatty liver disease"

Peter Chidiac received $539,515 (5 years) for the project, "Role of RGS2 in the response of cells to stress"

Lina Dagnino received $703,280 (5 years) for the project, "Integrin-linked kinase in epidermal stem cells"

Neil Duggal received $325,808 (4 years) for the project, "Metabolic and functional correlates in spinal cord compression measured by Magnetic Resonance Imaging"

Stefan Everling received $854,155 (5 years) for the project "Role of frontal cortical projection to the superior colliculus in saccade suppression and task switching in primates".

Stephen Ferguson received $758,070 (5 years) for the project "Regulation of Vascular G Protein-coupled Receptor Signal Transduction".

Amit Garg received funding for four projects:
$99,210 (2 years) for "Acute kidney injury from antiviral drugs for herpes infections: A population-based study of older adults"

$139,828 (2 years) for "Electrolyte Disorders from Common Medications: Risk and Mitigation"

$119,920 (2 years) for "Preoperative Medications and Acute Kidney Injury: A VISION sub-study"

$59,951 (1 year) for "Filtering Medline for Renal Information: Renal Sub-Filters"

Lakshman Gunaratnam received $100,000 (I year) for "Exploiting KIM-1 signalling to ameliorate acute kidney injury through clearance of apoptotic cells"

Daniel Hardy received $364,704 (3 years) for the project, "Molecular mechanisms underlying the in utero origins of hypercholesterolemia"

Robert Hegele received $599,814 (5 years) for the project, "Genetic architecture of cardiometabolic risk in families and communities"

David Heinrichs received $702,770 (5 years) for the project, "Role of iron and heme binding proteins in pathogenesis of Staphlococcus aureus"

David Holdsworth received $752,848 (5 years) for the project, "Single-plane dynamic radiography for quantification of bone and joint motion".

Anthony Jevnikar received $609,640 (5 years) for the project, "Regulation of renal tubular epithelial cell injury to promote kidney allograft survival".

John MacDonald received $1,048,740 (5 years) for his project "NMDA Receptors, Metaplasticity and Schizophrenia"

Mellissa Mann received $833,106 (5 years) for the project, "Molecular analysis of genomic imprint maintenance during embryogenesis"

Ravi Menon received $912,635 (5 years) for his project "Ultra high field MRI measurements of tissue magnetic susceptibility in Multiple Sclerosis".

Joseph Mymryk received $807,400 (5 years) for the project, "Molecular genetic analysis of adenovirus E1A function"

Giles Santyr received $367,905 (3 years) for his project "Functional and Metabolic Magnetic Resonance Imaging of Lung Inflammation".

Samuel Siu received $405,600 (3 years) for the project, "Pregnancy and Subsequent Cardiovascular Risk in Women with Heart Disease"

Rommel Tirona received $584,056 (4 years) for the project, "Role of Skeletal Muscle Drug Transporters in Statin-Induced Myopathy"

Ruud Veldhuizen received $100,000 (1 year) for "The effects of mechanical ventilation on the biophysical properties of pulmonary surfactant"

Hao Wang received $316,529 (3 years) for the project, "Mechanisms of Soluable CD83 in Prevention of Antibody Mediated Rejection"

Kaiping Yang received $566,323 (4 years) for the project, "Early-life origins of visceral adiposity"

Gregory Zaric received $173,829 (3 years) for his project "Economic evaluation of tests to reveal the source of cancers of unknown primary".