Stephen Pasternak
Assistant Professor
Scientist, Robarts Research Institute
Director, Cognitive Neurology and Alzheimer’s Disease Research Centre, Parkwood Institute
SB Massachusetts Institute of Technology Chemical Engineering
SB Massachusetts Institute of Technology Life Sciences
MD CM McGill University
PhD McGill University
FRCP(C) (Neurology)
Research Office: Robarts Research Institute Rm 3243
Phone: 519-931-5294
Clinical Office: Parkwood Institute, Main Building, RmA2-127
Phone: 519-646-6032
E-mail: spasternak@robarts.ca
Clinical Activities
Keywords: Neurodegenerative Disease, Alzheimer’s disease, Lewy Body Disease, Parksinon’s Disease Dementia
At my clinic at the Cognitive Neurology and Alzheimer's Disease Research Centre at Parkwood Hospital I specialize in the diagnosis and treatment of Neurodegenerative diseases, with a focus on Alzheimer’s disease, Lewy Body Disease, Parksinon’s Disease Dementia
Research Activities
Keywords: Neurodegenerative Disease, Alzheimer’s disease, Lewy Body Disease, Parksinon’s Disease Dementia, Clinical Trials; Cell Biology, beta Amyloid, Live Cell Imaging. Lysosomal Biology, Contrast agent development, Plasma Microparticles/exosomes.
At my laboratory at the Robarts Research Institute I am focused on understanding the basic cell biology of Alzheimer’s disease, using live cell imaging to study the role of intracellular protein trafficking on the production of beta-Amyloid. Other projects include developing Fluorescent and PET contrast agents for the diagnosis of Alzheimer’s disease, and developing diagnostic for Neurological disease tests based on microparticles in patient plasma samples. In the clinic, I have launched a Phase 2 Clinical Trial of Ambroxol in Parkinson’s Disease Dementia, and participate in academic and industry-sponsored clinical trials.
