Publications

Sancho M, Hald BO, Welsh DG. A stepwise approach to resolving small ionic currents in vascular tissue. Am J Physiol Heart Circ Physiol. 2020;318(3):H632-H638. doi:10.1152/ajpheart.00628.2019

Zechariah A, Tran CHT, Hald BO, et al. Intercellular Conduction Optimizes Arterial Network Function and Conserves Blood Flow Homeostasis During Cerebrovascular Challenges. Arterioscler Thromb Vasc Biol. 2020;40(3):733-750. doi:10.1161/ATVBAHA.119.313391

Sancho M, Fabris S, Hald BO, et al. Membrane Lipid-K_IR2.x Channel Interactions Enable Hemodynamic Sensing in Cerebral Arteries. Arterioscler Thromb Vasc Biol. 2019;39(6):1072-1087. doi:10.1161/ATVBAHA.119.312493

Sancho M, Gao Y, Hald BO, et al. An assessment of K_IR channel function in human cerebral arteries. Am J Physiol Heart Circ Physiol. 2019;316(4):H794-H800. doi:10.1152/ajpheart.00022.2019

Arpino JM, Nong Z, Li F, et al. Four-Dimensional Microvascular Analysis Reveals That Regenerative Angiogenesis in Ischemic Muscle Produces a Flawed Microcirculation. Circ Res. 2017;120(9):1453-1465. doi:10.1161/CIRCRESAHA.116.310535

Gros R, Van Uum, S, Ding QM, Pickering JG, Hegele RA, Feldman RD.  Increased enzyme activity and increased beta-adrenergic-mediated vasodilation in subjects expressing a single nucleotide variant of human adenylyl cyclase 6.  Arteriosclerosis Thrombosis and Vascular Biology 27:2657-2663, 2007.

Ho H, Hou G, Pickering JG, Hannigan G, Langille BL, Bendeck MP. Integrin linked kinase in the vascular smooth muscle cell response to injury. American Journal of Pathology 173:278-88, 2008.

Choi HY, Rahmani M, Wong BW, McManus BM, Pickering JG, Chan T, Francis GA. ABCA1 expression and apolipoprotein A-I binding are impaired in intimal-type arterial smooth muscle cells. Circulation 119:3223-31, 2009.

Frontini M, O'Neil C, Sawyez C, Chan BMC, Huff M, Pickering JG. Lipid Incorporation Inhibits Src-Dependent Assembly of Fibronectin and Type I Collagen by Vascular Smooth Muscle Cells. Circulation Research 104:832-41 2009. (Accompanied by Editorial)

Frontini, M. J., Nong, Z., Gros, R., Drangova, M., O'Neil, C., Rahman, M. N., Akawi, O., Yin, H., Ellis, C. G., and Pickering JG. (2011) Fibroblast growth factor 9 delivery during angiogenesis produces durable, vasoresponsive microvessels wrapped by smooth muscle cells. Nat Biotechnol. 29, 421-7.

Gris, P. Tighe, A., Levin, D., Sharma, R. andBrown A. (2007).  Transcriptional regulation of scar gene expression in primary astrocytes. Glia, 55(11):1145-55.

Gonzalez-Lara, L., Xu,K., Hofstetrova, K., Pniak, A.,Brown, A. and Foster P.  (2009).  In Vivo Magnetic Resonance Imaging of Spinal Cord Injury and Cell Therapy In Mice. J. Neurotrauma 26 (5): 753-62.

Marquardt, T., Gallarda1, B., Bonanomi1, D., Müller D.,Brown, A., Alaynick, W., Andrews, S.E., Lemke, G., and Pfaff, S. (2008).  Functional delineation of sensory and motor pathways via heterotypic trans-axonal signaling. Science, 230 (5873): 233-236.

Gris, P. Tighe, A., Hemphill, A., Thawer, S., Dekaban, G. andBrown A. (2009). Gene expression profiling in anti-CD11d mAb-treated spinal cord-injured rats. J Neuroimmunol. 209 (1-2):104-13.

Brown, A., Ricci, M-J. and Weaver L.C. (2007).  NGF mRNA is expressed in the dorsal root ganglia after spinal cord injury in the rat.  Experimental Neurology, 205(1):283-6.

Stephen, L.E., Fawkes, A., Pniak, K., Pniak, A., Lemke, G. and Brown, A.  (2007).  A critical role for the EphA3 receptor tyrosine kinase in heart development.  Developmental Biology, 302: 66-79.

Goodman RL, Lehman MN, Smith JT, Coolen LM, de Oliveira CV, Jafarzadehshirazi MR, Pereira A, Iqbal J, Caraty A, Ciofi P, Clarke IJ. (2007) Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B. Endocrinology. 148(12): 5752-60.

Bogusz AL, Hardy SL, Lehman MN, Connors JM, Hileman SM, Sliwowska JH, Billings HJ, McManus CJ, Valent M, Singh SR, Nestor CC,Coolen LM, Goodman RL (2008) Evidence that {gamma}-amino butyric acid is part of the neural circuit mediating estradiol negative feedback in anestrous ewes. Endocrinology. Jun;149(6):2762-72.

Jeremy T. Smith*,Lique M. Coolen*, Lance J. Kriegsfeld, Ika P. Sari, Mohammad R. Jaafarzadehshirazi, Matthew Maltby, Katherine Bateman, Robert L. Goodman, Alan J. Tilbrook, Takayoshi Ubuka, George E. Bentley, Iain J. Clarke, Michael N. Lehman (2008) Variation in kisspeptin and gonadotropin-inhibitory hormone expression and terminal connections to GnRH neurons in the brain: a novel medium for seasonal breeding in the sheep. Endocrinology, Nov;149(11):5770-82.

Sushma R. Singh, Stanley M. Hileman, John M. Connors, Christina J. McManus,Lique M. Coolen, Michael N. Lehman, and Robert L. Goodman (2009) Evidence that glutamatergic afferents to A15 dopaminergic neurons participate in estradiol negative feedback in the ewe and that this input varies with season.  150(10): 4663-71.

Guanliang Cheng,Lique M. Coolen*, Vasantha Padmanabhan, Robert L. Goodman, and Michael N. Lehman (2010) The kisspeptin/neurokinin B/dynorphin (KNDY) cell population of 1 the arcuate nucleus: sex differences and effects of prenatal testosterone in the sheep Endocrinology. 51(1):301-11.

Marcel Amstalden, Lique M. Coolen, Ann M. Hemmerle, Heather J. Billings, Christie J. McManus, Miro Valent, Robert L. Goodman, Michael N. Lehman(2010) Neurokinin 3 receptor immunoreactivity in the septal region, preoptic area and hypothalamus of the sheep: colocalization in neurokinin B cells of the arcuate nucleus but not in gonadotropin-releasing hormone neurons. Neuroendocrinol. 22(1):1-12.

Karla S. Frohmader, Joost Wiskerke, Roy A.Wise, Michael N. Lehman, andLique M. Coolen (2010) Methamphetamine acts on neurons regulating sexual behavior in male rats. Neurosci. In Press.

Davis, J.F., Loos, M., Di Sebastiano A.R., Brown J.L., and Coolen L.M. (2010) Lesions of the Medial Prefrontal Cortex Abolish Conditioned Aversion Associated with Sexual Behavior in Male Rats.  Psych. In Press

Lehman M.N., Ladha Z.,Coolen L.M., Hileman S.M., Connors J.M., Goodman R.L. (2010)  Neuronal plasticity and seasonal reproduction in sheep. Eur J Neurosci. 32(12):2152-64.

Amstalden M.,Coolen L.M., Hemmerle A.M., Billings H.J., Connors J.M., Goodman R.L., Lehman M.N. (2010) Neurokinin 3 receptor immunoreactivity in the septal region, preoptic area and hypothalamus of the female sheep: colocalisation in neurokinin B cells of the arcuate nucleus but not in gonadotrophin-releasing hormone neurones. J Neuroendocrinol. 22(1):1-12.

Staudt M.D., de Oliveira C.V., Lehman M.N., McKenna K.E.,Coolen L.M. (2011) Activation of NMDA receptors in lumbar spinothalamic cells is required for ejaculation. J Sex Med. 8(4):1015-26.

Goodman RL, Maltby MJ, Millar RP, Hileman SM, Nestor CC, Whited B, Tseng AS,Coolen LM, Lehman MN. (2012) Evidence that dopamine acts via kisspeptin to hold GnRH pulse frequency in check in anestrous ewes. Endocrinology. Dec;153(12):5918-27

Reale ME, Webb IC, Wang X, Baltazar RM,Coolen LM, Lehman MN. (2013) The transcription factor Runx2 is under circadian control in the suprachiasmatic nucleus and functions in the control of rhythmic behavior. PLoS One 8(1):e54317.

Pitchers KK, Vialou V, Nestler EJ, Laviolette SR, Lehman MN,Coolen LM. (2013) Natural and drug rewards act on common neural plasticity mechanisms with ΔFosB as a key mediator. J Neurosci. Feb 20;33(8):3434-42

Nestor CC, Coolen LM, Nesselrod GL, Valent M, Connors JM, Hileman SM, Cheng G, Lehman MN, Goodman RL. (2013) Evidence that Orphanin FQ Mediates Progesterone Negative Feedback in the Ewe. Endocrinology, Aug 8 [Epub ahead of print]

Gonzalez YR, Zhang Y, Behzadpoor D,Cregan S, Bamforth S, Slack RS, and Park DS (2008), CITED2 signals through PPARgamma to regulate death of cortical neurons after DNA damage. J Neurosci. 28(21):5559-5569.

Zhang Y, Parsanejad M, Qu D, Aleyasin H, Rodriguez-Gonzalez Y, Slack R,Cregan SP,  and Park DS (2009), Pim-1 kinase is an activator of the cell cycle pathway in neuronal death induced by DNA damage. J Neurochem 112(2):497-510.

Steckley, D., Karajgikar, M., Dale, L. B., Swan, P., Fuerth, B., Drummond-Main, C.,Poulter, M. O., Ferguson, S. S. G., Strasser, A., and Cregan, S. P. (2007) Puma is a Dominant Regulator of Oxidative Stress Induced Bax Activation and Neuronal Apoptosis. J. Neurosci. 27, 12989-12999.

Biswas SC, Zhang Y, Iyirhiaro G, Willett R, Rodriguez-Gonzalez,Cregan SP, Slack RS, Park DS, and Greene LA (2010), SERTAD1 plays an essential role in development and pathological neuron death. J Neurosci in press

Dekaban, G.A., Snir, J., Shrum, B., de Chickera, S., Willert, C., Said E.A., Sékaly, R.P., Foster, P.J., O’Connell, P.J. Semi-quantitation of mouse dendritic cell migration in vivo using cellular MRI.  J. Immunotherapy, 32: 240-251, 2009

Adeyanju, K., Krizova, A., Gilbert, P.A.,Dekaban, G.A., Rieder, M.A. HIV Tat potentiates cell toxicity in a T cell model of a sulphamethoxazole-induced adverse drug reaction.  Virus Genes, 38: 372-382 (2009). 

McKillop, W.M., *Barrett, J.W., Chan, B.,Dekaban, G.A.  The extracellular domain of the CD11d integrin regulates cell surface expression.  Journal of Leukocyte Biol. (2009) 86: 851-62. 

Barrett, J., Werden, S.J., Wang, F., McKillop, W.M., Jimenez, J., Villeneuve, D., McFadden, G.,Dekaban, G.A., Myxoma virus M130R is a novel virulence factor required for lethal myxomatosis in rabbits. Virus Research (2009). 

Mumin AM, Barrett JW, Dekaban GA, Zhang J. (2011) Dendritic cell internalization of foam-structured fluorescent mesoporous silica nanoparticles. J Colloid Interface Sci. Jan 1;353(1):156-62

Mawhinney LA, Thawer SG, Lu WY, Rooijen Nv, Weaver LC, Brown A,Dekaban GA. (2012) Differential detection and distribution of microglial and hematogenous macrophage populations in the injured spinal cord of lys-EGFP-ki transgenic mice. J Neuropathol Exp Neurol. Mar;71(3):180-97.

Zheng X, Vladau C, Zhang X, Suzuki M, Ichim TE, Zhang ZX, Li M, Carrier E, Garcia B, Jevnikar AM, Min WP: A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation.  Blood 2009;113:2646-2654.

Wang H, Ge W, Arp J, Zassoko R, Liu W, Ichim TE, Jiang J, Jevnikar AM, Garcia B: Free bone graft attenuates acute rejection and in combination with cyclosporin leads to indefinite cardiac allograft survival.  J Immunol 2009;182:5970-5981.

Zheng X, Lian D, Wong A, Bygrave M, Ichim TE, Khoshniat M, Zhang X, Sun H, DeZordo T, Lacefield JC, Garcia B, Jevnikar AM, Min WP: Novel small interfering RNA-containing solution protecting donor organs in heart transplantation.  Circulation 2009:120(12): 1099-1107.

Lahiry P, Wang J, Robinson JF, Turowec JP, Litchfield DW, Lanktree MB, Gloor GB, Puffenberger EG, Strauss KA, Martens MB, Ramsay DA, Rupar CA, Siu V, Hegele RA. (2009) A multiplex human syndrome implicates a key role for intestinal cell kinase in development of central nervous, skeletal, and endocrine systems. Am J Hum Genet. 84(2):134-47.

St-Denis NA, Derksen DR, Litchfield DW. (2009) Evidence for regulation of mitotic progression through temporal phosphorylation and dephosphorylation of CK2alpha. Mol Cell Biol. 29(8):2068-81.

Mohan RD, Litchfield DW, Torchia J, Tini M. (2009) Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase. Nucleic Acids Res. 2009 Dec 4. [Epub ahead of print ]

Mohan RD, Litchfield DW, Torchia J, Tini M. (2010) Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase. Nucleic Acids Res. 38(4):1135-48.

Bragdon B., Thinakaran S., Moseychuk O., King D., Young K., Litchfield D.W., Petersen N.O., Nohe A.(2010) Casein kinase 2 beta-subunit is a regulator of bone morphogenetic protein 2 signaling. Biophys J. 99(3):897-904.

St-Denis N.A., Bailey M.L., Parker E.L., Vilk G., Litchfield D.W. (2011) Localization of phosphorylated CK2alpha to the mitotic spindle requires the peptidyl-prolyl isomerase Pin1. J Cell Sci. 124(Pt 14):2341-8.

Bae J.J., Xiang Y.Y., Martinez-Canabal A., Frankland P.W., Yang B.B., Lu W.Y. (2011) Increased transforming growth factor-β1 modulates glutamate receptor expression in the hippocampus. Int J Physiol Pathophysiol Pharmacol. 3(1):9-20.

Kimura T., Kawabe H., Jiang C., Zhang W., Xiang Y.Y., Lu C., Salter M.W., Brose N., Lu W.Y., Rotin D.(2011) Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease. Proc Natl Acad Sci U S A. 108(8):3216-21

Bae JJ, Xiang YY, Martinez-Canabal A, Frankland PW, Yang BB, Lu WY. (2011) Increased transforming growth factor-β1 modulates glutamate receptor expression in the hippocampus. Int J Physiol Pathophysiol Pharmacol. 2011;3(1):9-20.

Wang S, Xiang YY, Ellis R, Wattie J, Feng M, Inman MD, Lu WY. (2011) Effects of furosemide on allergic asthmatic responses in mice. Clin Exp Allergy. Oct;41(10):1456-67.

Li Y, Xiang YY, Lu WY, Liu C, Li J. (2012) A novel role of intestine epithelial GABAergic signaling in regulating intestinal fluid secretion. Am J Physiol Gastrointest Liver Physiol. Aug 15;303(4):G453-60.

Xiang YY, Chen X, Li J, Wang S, Faclier G, Macdonald JF, Hogg JC, Orser BA, Lu WY. (2013) Isoflurane regulates atypical type-A γ-aminobutyric acid receptors in alveolar type II epithelial cells. Anesthesiology. May;118(5):1065-75.

Feng MM, Xiang YY, Wang S, Lu WY. (2013) Total chemical synthesis of dengue 2 virus capsid protein via native chemical ligation: role of the conserved salt-bridge. Bioorg Med Chem. Jun 15;21(12):3443-9

Christie D.A., Lemke C.D., Elias I.M., Chau L.A., Kirchhof M.G., Li B., Ball E.H., Dunn S.D., Hatch G.M., Madrenas J. (2011) Stomatin-like protein 2 binds cardiolipin and regulates mitochondrial biogenesis and function. Mol Cell Biol. 31(18):3845-56.

Christie DA, Kirchhof MG, Vardhana S, Dustin ML, Madrenas J. (2012) Mitochondrial and plasma membrane pools of stomatin-like protein 2 coalesce at the immunological synapse during T cell activation. PLoS One.7(5):e37144.

Li, C., J.I.S. MacDonald, T. Hryciw and S.O. Meakin. 2010. Nerve Growth Factor Activation of the TrkA Receptor Induces Cell Death, by Macropinocytosis, in Medulloblastoma Daoy Cells.  Journal of Neurochemistry. 112: 882-899

Li, C., J.I.S. MacDonald, T. Hryciw and S.O. Meakin. 2010. Nerve Growth Factor Activation of the TrkA Receptor Induces Cell Death, by Macropinocytosis, in Medulloblastoma Daoy Cells.  Journal of Neurochemistry. 112: 882-899

Hryciw, T., J.I.S. MacDonald, R. Phillips, C. Seah, S. Pasternak and S.O. Meakin. 2010.  The Fibroblast Growth Factor Receptor Substrate 3 (Frs3) is a Developmentally Regulated Microtubule-Associated Protein Expressed in Migrating and Differentiated Neurons.  J. of Neurochemistry. 112: 924-939.

MacDonald JI, Dietrich A, Gamble S, Hryciw T, Grant RI, Meakin SO. (2012) Nesca, a novel neuronal adapter protein, links the molecular motor kinesin with the pre-synaptic membrane protein, syntaxin-1, in hippocampal neurons. J Neurochem. Jun;121(6):861-80

Lorenzen, A., Vandewark, K., Samosh, J., Anborgh, P. H., Seah, C., Magalhaes, A. C., Cregan, S. P. Ferguson S. S. G. and Pasternak S. H. (2010) Rapid and direct transport of cell surface APP to the lysosome defines a novel, selective pathway. Mol. Brain. 3, 11.

Suchý M., Ta R., Li A.X., Wojciechowski F., Pasternak S.H., Bartha R., Hudson R.H. (2010) A paramagnetic chemical exchange-based MRI probe metabolized by cathepsin D: design, synthesis and cellular uptake studies. Org Biomol Chem. 8(11):2560-6.

Ta R, Suchy M, Tam JH, Li AX, Martinez-Santiesteban FS, Scholl TJ, Hudson RH, Bartha R, Pasternak SH. (2013) A dual magnetic resonance imaging/fluorescent contrast agent for Cathepsin-D detection. Contrast Media Mol Imaging. Mar-Apr;8(2):127-39

Anisman H., Prakash P., Merali Z., Poulter M.O. Corticotropin releasing hormone receptor alterations elicited by acute and chronic unpredictable stressor challenges in stressor-susceptible and resilient strains of mice. Behav Brain Res. 181,180-90, 2007.

Gavrilovici C., D’Alfonso S. and Poulter M.O. Diverse interneuron populations have highly specific interconnectivity in the rat piriform cortex J Comp Neurol. In Press

Steiner J.P., Payne K., D’Alfonso S., Jacobson K., Hicks T. P., Hamilton G., Staines W. and Poulter M.O. (2010) GPI-1046 increases presenilin-1 expression and restores NMDA channel activity. Can J Neurol Sci. 2010 Jul;37(4):457-67.

Kia A, Ribeiro F, Nelson R, Gavrilovici C, Ferguson SS, Poulter MO. (2011) Kindling alters neurosteroid-induced modulation of phasic and tonic GABAA receptor-mediated currents: role of phosphorylation. J Neurochem. Mar;116(6):1043-56.

Gavrilovici C, Pollock E, Everest M, Poulter MO. (2012) The loss of interneuron functional diversity in the piriform cortex after induction of experimental epilepsy. Neurobiol Dis. Dec;48(3):317-28.

Ribeiro, F. M., Ferreira, L. T., Marion, S., Fontes, S., Gomez, M.V., Ferguson, S.S.G., Prado M.A.M., and. Prado, V.F (2007) SEC14-like protein 1 interacts with cholinergic transporters. Neurochem. Int. 50, 356-364.

Caetano FA, Lopes MH, Haijj GNM, Machado CF, Arantes CP, Magalhães AC, Vieira MPB Américo TA, Massensini AR, Priola SA, Vorberg I, Gomez MV, Linden R, Prado VF, Martins VR, Prado MAM (2008) Prion protein endocytosis is required for ERK 1/2 signaling induced by stress-inducible protein. Journal of Neuroscience 28: 6691-6702

de Castro, B.M.; Pereira, G.S.; Magalhães, V.; Rossato, J.I.; de Jaeger, X.; Martins-Silva, C.; Leles, B.; Lima, P.; Gomez, M.V.; Gainetdinov, R.R.; Caron, M.G.; Izquierdo, I.; Cammarota, M.; Prado, V.F.; Prado, M.A.M. (2009) Reduced expression of the vesicular acetylcholine transporter causes learning deficits in mice. Genes, Brain and Behavior 8: 23-35.

Amaral E, Leite LF, Gomez MV, Prado M.A.M, Guatimosim C. (2009)  Ouabain evokes exocytosis dependent on ryanodine and mitochondrial calcium stores that is not followed by compensatory endocytosis at the neuromuscular junction Neurochemistry International  55: 406-13.

De Castro, B; De Jaeger, X; Martins-Silva, C.; Lima, R.F.; Amaral, E.; Menezes, C.; Lima, P.; Neves, C.M.L; Gould, T.W.; Welch, I; Kushmeric, C.; Guatimosim, C.; Izquierdo,I.; Cammarota, M.; Rylett, R.J.; Gomez, M.V.; Caron, M.G.; Oppenheim, R.W.; Prado, M.A.M*.; Prado, V.F*.  (2009)  The vesicular acetylcholine transporter is required for neuromuscular development and function. Molecular and Cellular Biology 29: 5238-50.

Beraldo F.H., Arantes C.P., Santos T.G., Machado C.F., Roffe M., Hajj G.N., Lee K.S., Magalhães A.C., Caetano F.A., Mancini G.L., Lopes M.H., Américo T.A., Magdesian M.H., Ferguson S.S., Linden R., Prado M.A., Martins V.R. (2011) Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain. FASEB 25(1):265-79. 

Guzman MS, De Jaeger X, Raulic S, Souza IA, Li AX, Schmid S, Menon RS, Gainetdinov RR, Caron MG, Bartha R, Prado VF, Prado MA. (2011) Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission. PLoS Biol. Nov;9(11):e1001194.

Roy A, Lara A, Guimarães D, Pires R, Gomes ER, Carter DE, Gomez MV, Guatimosim S, Prado VF, Prado MA, Gros R. (2012) An analysis of the myocardial transcriptome in a mouse model of cardiac dysfunction with decreased cholinergic neurotransmission. PLoS One.7(6):e39997

Santos TG, Beraldo FH, Hajj GN, Lopes MH, Roffe M, Lupinacci FC, Ostapchenko VG, Prado VF, Prado MA, Martins VR. (2013) Laminin-γ1 chain and stress inducible protein 1 synergistically mediate PrPC-dependent axonal growth via Ca2+ mobilization in dorsal root ganglia neurons. J Neurochem. Jan 124(2):210-23.

Ostapchenko VG, Beraldo FH, Guimarães AL, Mishra S, Guzman M, Fan J, Martins VR, Prado VF, Prado MA. (2013) Increased prion protein processing and expression of metabotropic glutamate receptor 1 in a mouse model of Alzheimer's disease. J Neurochem. May 8 [Epub ahead of print]

Beraldo FH, Soares IN, Goncalves DF, Fan J, Thomas AA, Santos TG, Mohammad AH, Roffé M, Calder MD, Nikolova S, Hajj GN, Guimaraes AL, Massensini AR, Welch I, Betts DH, Gros R, Drangova M, Watson AJ, Bartha R, Prado VF, Martins VR, Prado MA. (2013) Stress-inducible phosphoprotein 1 has unique cochaperone activity during development and regulates cellular response to ischemia via the prion protein. FASEB J. Sep;27(9):3594-607

Roy A, Fields WC, Rocha-Resende C, Resende RR, Guatimosim S, Prado VF, Gros R, Prado MA. (2013) Cardiomyocyte-secreted acetylcholine is required for maintenance of homeostasis in the heart. FASEB J. Sep 9. [Epub ahead of print]

Soares IN, Caetano FA, Pinder J, Roz Rodrigues B, Beraldo FH, Ostapchenko VG, Durette C, Schenatto Pereira G, Lopes MH, Queiroz-Hazarbassanov N, Cunha IW, Sanematsu PI, Suzuki S, Bleggi-Torres LF, Schild-Poulter C, Thibault P, Dellaire G, Martins VR, Prado VF, Prado MA.(2013) Regulation of stress-inducible phosphoprotein 1 nuclear retention by PIAS1. Mol Cell Proteomics. 2013 Aug 12. [Epub ahead of print]

Ostrakhovitch EA, Semenikhin OA.(2011) p53-mediated regulation of neuronal differentiation via regulation of dual oxidase maturation factor 1. Neurosci Lett. 494(1):80-5.

Sanelli T, Strong MJ. (2007) Loss of nitric oxide-mediated down-regulation of NMDA receptors in neurofilament aggregate-bearing motor neurons in vitro: implications for motor neuron disease. Free Radic Biol Med. 42(1):143-51

Sanelli T, Ge W, Leystra-Lantz C, Strong MJ. (2007) Calcium mediated excitotoxicity in neurofilament aggregate-bearing neurons in vitro is NMDA receptor dependant. J Neurol Sci. 256(1-2):39-51.

Strong MJ, Volkening K, Hammond R, Yang W, Strong W, Leystra-Lantz C, Shoesmith C. (2007) TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein. Mol Cell Neurosci. 35(2):320-327.

Robertson J, Sanelli T, Xiao S, Yang W, Horne P, Hammond R, Pioro EP, Strong MJ. (2007) Lack of TDP-43 abnormalities in mutant SOD1 transgenic mice shows disparity with ALS. Neurosci Lett. 13;420(2):128-32.

Kesavapany S, Patel V, Zheng YL, Pareek TK, Bjelogrlic M, Albers W, Amin N, Jaffe H, Gutkind JS, Strong MJ, Grant P, Pant HC. (2007) Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons.Mol Biol Cell. 18(9):3645-55.

Yang W, Leystra-Lantz C, Strong MJ. (2008) Upregulation of GSK3beta expression in frontal and temporal cortex in ALS with cognitive impairment (ALSci). Brain Res. 27;1196:131-9

Xiao S, Tjostheim S, Sanelli T, McLean JR, Horne P, Fan Y, Ravits J, Strong MJ, Robertson J. (2008) An aggregate-inducing peripherin isoform generated through intron retention is upregulated in amyotrophic lateral sclerosis and associated with disease pathology. J Neurosci. 28(8):1833-40

Gohar M, Yang W, Strong W, Volkening K, Leystra-Lantz C, Strong MJ. (2009) Tau phosphorylation at threonine-175 leads to fibril formation and enhanced cell death: implications for amyotrophic lateral sclerosis with cognitive impairment.J Neurochem. 108(3):634-43.

Moisse K, Volkening K, Leystra-Lantz C, Welch I, Hill T, Strong MJ. (2009) Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury.Brain Res. 2009 Jan 16;1249:202-11.

Humayun S, Gohar M, Volkening K, Moisse K, Leystra-Lantz C, Mepham J, McLean J, Strong MJ. (2009) The complement factor C5a receptor is upregulated in NFL-/- mouse motor neurons. J Neuroimmunol. 210(1-2):52-62.

Moisse K, Mepham J, Volkening K, Welch I, Hill T, Strong MJ. (2009) Cytosolic TDP-43 expression following axotomy is associated with caspase 3 activation in NFL-/- mice: support for a role for TDP-43 in the physiological response to neuronal injury.Brain Res. 1296:176-86

Volkening K, Leystra-Lantz C, Yang W, Jaffee H, Strong MJ. (2009) Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS). Brain Res. 1305:168-82.

Keller BA, Volkening K, Droppelmann CA, Ang LC, Rademakers R, Strong MJ. (2012) Co-aggregation of RNA binding proteins in ALS spinal motor neurons: evidence of a common pathogenic mechanism. Acta Neuropathol. Nov;124(5):733-47

Marolda CL, Tatar LD, Alaimo C, Aebi M, Valvano MA. (2007) Interplay of the Wzx translocase and the corresponding polymerase and chain length regulator proteins in the translocation and periplasmic assembly of lipopolysaccharide o antigen. J Bacteriol188(14):5124-35

Ha SD, Ng D, Lamothe J, Valvano MA, Han J, Kim SO. (2007) Mitochondrial proteins Bnip3 and Bnip3L are involved in anthrax lethal toxin-induced macrophage cell death. J Biol Chem. 282(36):26275-83.

Keith KE, Killip L, He P, Moran GR, Valvano MA. (2007) Burkholderia cenocepacia C5424 produces a pigment with antioxidant properties using a homogentisate intermediate. J Bacteriol. 189(24):9057-65.

Flannagan RS, Valvano MA. (2008) Burkholderia cenocepacia requires RpoE for growth under stress conditions and delay of phagolysosomal fusion in macrophages. Microbiology. 154(Pt 2):643-53.

Saldías MS, Lamothe J, Wu R, Valvano MA. (2008) Burkholderia cenocepacia requires the RpoN sigma factor for biofilm formation and intracellular trafficking within macrophages. Infect Immun. 76(3):1059-67.

Aubert DF, Flannagan RS, Valvano MA. (2008) A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.Infect Immun. 76(5):1979-91

Lamothe J, Valvano MA. (2008) Burkholderia cenocepacia-induced delay of acidification and phagolysosomal fusion in cystic fibrosis transmembrane conductance regulator (CFTR)-defective macrophages. Microbiology. 154(Pt 12):3825-34

Keith KE, Hynes DW, Sholdice JE, Valvano MA. (2009) Delayed association of the NADPH oxidase complex with macrophage vacuoles containing the opportunistic pathogen Burkholderia cenocepacia.Microbiology. 155(Pt 4):1004-15

Ortega X, Silipo A, Saldías MS, Bates CC, Molinaro A, Valvano MA. (2009) Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide: truncation of the core oligosaccharide leads to increased binding and sensitivity to polymyxin B. J Biol Chem. 284(32):21738-51

Saldías MS, Ortega X, Valvano MA. (2009) Burkholderia cenocepacia O antigen lipopolysaccharide prevents phagocytosis by macrophages and adhesion to epithelial cells.J Med Microbiol. 58(Pt 12):1542-8.

Huynh K,K,, Plumb J,D,, Downey G,P,, Valvano M,A,, Grinstein S.(2010) Inactivation of macrophage Rab7 by Burkholderia cenocepacia. J Innate Immun. 2(6):522-33.Rosales-

Reyes R, Skeldon AM, Aubert DF, Valvano MA.(2012) The Type VI secretion system of Burkholderia cenocepacia affects multiple Rho family GTPases disrupting the actin cytoskeleton and the assembly of NADPH oxidase complex in macrophages. Cell Microbiol. Feb;14(2):255-73

Rosales-Reyes R, Aubert DF, Tolman JS, Amer AO, Valvano MA. (2012) Burkholderia cenocepacia type VI secretion system mediates escape of type II secreted proteins into the cytoplasm of infected macrophages. PLoS One.7(7):e41726.