Dr. Merrick Zwarenstein Peer Reviewed Publications

Kahan BC, Hall SS, Beller EM, Birchenall M, Chan AW, Elbourne D, Little P, Fletcher J, Golub RM, Goulao B, Hopewell S, Islam N, Zwarenstein M, Juszczak E, Montgomery AA. Reporting of Factorial Randomized Trials: Extension of the CONSORT 2010 Statement. JAMA, 2023 Dec 5; 330 (21): 2106-2114, Coauthor, DOI: 10.1001/jama.2023.19793.

Kahan BC, Hall SS, Beller EM, Birchenall M, Elbourne D, Juszczak E, Little P, Fletcher J, Golub RM, Goulao B, Hopewell S, Islam N, Zwarenstein M, Chan A-W, Montgomery AA. Consensus Statement for Protocols of Factorial Randomized Trials: Extension of the SPIRIT 2013 Statement. JAMA Netw Open, 2023 Dec 5; 6 (12:1): e234612, Coauthor, DOI: 10.1001/jamanetworkopen.2023.46121.

Yazdani Y, Garg AX, Zwarenstein M. Integrating Specialist and Primary Care in Chronic Disease Management. JAMA Intern Med. 2024 Apr 15. doi: 10.1001/jamainternmed.2024.0873. Online ahead of print. PMID: 38619835.

Nash DM, Thorpe C, Brown JB, Kueper JK, Rayner J, Lizotte DJ, Terry AL, Zwarenstein M. Perceptions of Artificial Intelligence Use in Primary Care: A Qualitative Study with Providers and Staff of Ontario Community Health Centres J Am Board Fam Med March/April 2023; 36:221-228; doi:10.3122/jabfm.2022.220177R.

Ben Charif A, Zomahoun HTV, Gogovor A, Abdoulaye Samri M, Massougbodji J, Wolfenden L, Ploeg J, Zwarenstein M, Milat AJ, Rheault N, Ousseine YM, Salerno J, Markle-Reid M, Légaré F. Tools for assessing the scalability of innovations in health: a systematic review. Health Res Policy Syst. 2022 Mar 24;20(1):34. doi: 10.1186/s12961-022-00830-5.

Giraudeau B, Caille A, Eldridge SM, Weijer C, Zwarenstein M, Taljaard M. Heterogeneity in pragmatic randomised trials: sources and management. BMC Med. 2022 Oct 28;20(1):372. doi: 10.1186/s12916-022-02569-w.

Howard M, Pfaff K, Sattler D, Dolovich L, Marshall D, Zwarenstein M, Upshur R. Achieving holistic, quality-of-life focused care: description of a Compassion Care Community initiative in Canada. Health Promot Int. 2022 Jun 1;37(3):daac067. doi: 10.1093/heapro/daac067.

Kueper J.K.; Rayner J.; Zwarenstein M.; Lizotte D.J. Describing a complex primary health care population to support future decision support initiatives. International Journal of Population Data Science. Open Access. Volume 7, Issue 1, 2022, Article number 21. doi: 10.23889/IJPDS.V7I1.1756.

Kueper JK, Terry A, Bahniwal R, Meredith L, Beleno R, Brown JB, Dang J, Leger D, McKay S, Pinto A, Ryan BL, Zwarenstein M, Lizotte DJ. Connecting artificial intelligence and primary care challenges: findings from a multi stakeholder collaborative consultation. BMJ Health Care Inform. 2022 Jan;29(1):e100493. doi: 10.1136/bmjhci-2021-100493.

Liang A, Cirone KD, Deng XD, Zwarenstein M. The relationship between pragmatism, timing, and study size on impact of treatment trials: a qualitative, hypothesis generating study of systemic corticosteroids for COVID-19. J Clin Epidemiol. 2022 Oct 6: S0895-4356(22)00239-6. doi: 10.1016/j.jclinepi.2022.09.018. Online ahead of print.

Nash DM, Brown JB, Thorpe C, Rayner J, Zwarenstein M. The Alliance for Healthier Communities as a Learning Health System for primary care: A qualitative analysis in Ontario, Canada. J Eval Clin Pract. 2022 Apr 30. doi: 10.1111/jep.13692. Epub ahead of print.

Sharma T, Qamar I, Zwarenstein M. How pragmatic are randomized trials of Remdesivir and Favipiravir for in-hospital treatment of Covid-19: A descriptive methodological review of trial design using the PRECIS-2 framework. J Clin Epidemiol. 2022 Oct 18:S0895-4356(22)00260-8. doi: 10.1016/j.jclinepi.2022.10.013. Epub ahead of print.

Shuldiner J.; Schwartz K.L.; Langford B.J.; Ivers N.M.; Taljaard M.; Grimshaw J.M.; Lacroix M.; Tadrous M.; Leung V.; Brown K.; Morris A.M.; Garber G.; Presseau J.; Thavorn K.; Leis J.A.; Witteman H.O.; Brehaut J.; Daneman N.; Silverman M.; Greiver M.; Gomes, T.; Kidd, M.R.; Francis, J.; Zwarenstein, M.; Lam, J.; Mulhall, C.; Gushue, S.; Uppal, S.; Wong, A. Optimizing responsiveness to feedback about antibiotic prescribing in primary care: protocol for two interrelated randomized implementation trials with embedded process evaluations. Implementation Science. Open Access. Volume 17, Issue 1, December 2022, Article Number 17. doi: 10.1186/s13012-022-01194-8.

Taljaard M, Nicholls SG, Howie AH, Nix HP, Carroll K, Moon PM, Nightingale NM, Giraudeau B, Hey SP, Eldridge SM, Weijer C, Zwarenstein M. An analysis of published trials found that current use of pragmatic trial labels is uninformative. J Clin Epidemiol. 2022 Aug 18; 151:113-121. doi: 10.1016/j.jclinepi.2022.08.007. Online ahead of print.

Terry AL, Kueper JK, Beleno R, Brown JB, Cejic S, Dang J, Leger D, McKay S, Meredith L, Pinto AD, Ryan BL, Stewart M, Zwarenstein M, Lizotte DJ. Is primary health care ready for artificial intelligence? What do primary health care stakeholders say? BMC Med Inform Decis Mak, 2022 Sep 9; 22 (1): 237, DOI: 10.1186/s12911-022-01984-6.

Fortin M, Stewart M, Ngangue P, Almirall J, Bélanger M, Brown JB, Couture M, Gallagher F, Katz A, Loignon C, Ryan BL, Sampalli T, Wong ST, Zwarenstein M. Scaling Up Patient-Centered Interdisciplinary Care for Multimorbidity: A Pragmatic Mixed-Methods Randomized Controlled Trial. Ann Fam Med. 2021 Mar-Apr;19(2):126-134. doi: 10.1370/afm.2650

Cord KAM, Imran M, Rice DB, McCall SJ, Kwakkenbos L, Sampson M, Fröbert O, Gale C, Langan SM, Moher D, Relton C, Zwarenstein M, Juszczak E, Thombs BD; CONSORT Extension for Trials Conducted Using Cohorts and Routinely Collected Data Group. Reporting Transparency and Completeness in Trials: Paper 2 - Reporting of randomised trials using registries was often inadequate and hindered the interpretation of results. J Clin Epidemiol. 2021 Sep 12:S0895-4356(21)00292-4. doi: 10.1016/j.jclinepi.2021.09.012. Epub ahead of print.

Dixon SN, Sontrop JM, Al-Jaishi A, Killin L, McIntyre CW, Anderson S, Bagga A, Benjamin D, Blake P, Devereaux PJ, Iliescu E, Jain A, Lok CE, Nesrallah G, Oliver MJ, Pandeya S, Sood MM, Tam P, Wald R, Walsh M, Zwarenstein M, Garg AX. MyTEMP: Statistical Analysis Plan of a Registry-Based, Cluster-Randomized Clinical Trial. Can J Kidney Health Dis. 2021 Aug 27;8:20543581211041182. doi: 10.1177/20543581211041182.

Fortin M, Stewart M, Almirall J, Berbiche D, Bélanger M, Katz A, Ryan BL, Wong ST, Zwarenstein M. One year follow-up and exploratory analysis of a patient-centered interdisciplinary care intervention for multimorbidity. J Comorb. 2021 Nov 17;11:26335565211039780. doi: 10.1177/26335565211039780.

Fortin M, Stewart M, Ngangue P, Almirall J, Bélanger M, Brown JB, Couture M, Gallagher F, Katz A, Loignon C, Ryan BL, Sampalli T, Wong ST, Zwarenstein M. Scaling Up Patient-Centered Interdisciplinary Care for Multimorbidity: A Pragmatic Mixed-Methods Randomized Controlled Trial. Ann Fam Med. 2021 Mar-Apr;19(2):126-134. doi: 10.1370/afm.2650.

Howie A, Taljaard M, Moon PM, Nightingale N, Zwarenstein M. Addressing the disconnect between trial intention and design. Lancet Glob Health. 2021 May;9(5):e577-e578. doi: 10.1016/S2214-109X(20)30543-X. Epub 2021 Jan 15.

Howie AH, Klar N, Nash DM, Reid JN, Zwarenstein M. Printed educational materials directed at Ontario family physicians do not improve adherence to guideline recommendations for diabetes management: a pragmatic, factorial, cluster randomized controlled trial [ISRCTN72772651]. BMC Fam Pract. 2021 Dec 11;22(1):243. doi: 10.1186/s12875-021-01592-9.

Imran M, Kwakkenbos L, McCall SJ, McCord KA, Fröbert O, Hemkens LG, Zwarenstein M, Relton C, Rice DB, Langan SM, Benchimol EI, Thabane L, Campbell MK, Sampson M, Erlinge D, Verkooijen HM, Moher D, Boutron I, Ravaud P, Nicholl J, Uher R, Sauvé M, Fletcher J, Torgerson D, Gale C, Juszczak E, Thombs BD. Methods and results used in the development of a consensus-driven extension to the Consolidated Standards of Reporting Trials (CONSORT) statement for trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE). BMJ Open. 2021 Apr 29;11(4):e049093. doi: 10.1136/bmjopen-2021-049093

Imran M, Cord KM, McCall SJ, Kwakkenbos L, Sampson M, Fröbert O, Gale C, Hemkens LG, Langan SM, Moher D, Relton C, Zwarenstein M, Juszczak E, Thombs BD, On Behalf Of Consort Extension For Trials Conducted Using Cohorts And Routinely Collected Data Group. Reporting Transparency and Completeness in Trials: Paper 3 - Trials conducted using administrative databases do not adequately report elements related to use of databases. J Clin Epidemiol. 2021 Sep 11:S0895-4356(21)00290-0. doi: 10.1016/j.jclinepi.2021.09.010. Epub ahead of print.

Kwakkenbos L, Imran M, McCall SJ, McCord KA, Fröbert O, Hemkens LG, Zwarenstein M, Relton C, Rice DB, Langan SM, Benchimol EI, Thabane L, Campbell MK, Sampson M, Erlinge D, Verkooijen HM, Moher D, Boutron I, Ravaud P, Nicholl J, Uher R, Sauvé M, Fletcher J, Torgerson D, Gale C, Juszczak E, Thombs BD. CONSORT extension for the reporting of randomised controlled trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE): checklist with explanation and elaboration. BMJ. 2021 Apr 29;373:n857. doi: 10.1136/bmj.n857

McCall SJ, Imran M, Hemkens LG, Cord KM, Kwakkenbos L, Sampson M, Jawad S, Zwarenstein M, Relton C, Langan SM, Moher D, Fröbert O, Thombs BD, Gale C, Juszczak E. Reporting Transparency and Completeness in Trials: Paper 4 - Reporting of randomised controlled trials conducted using routinely collected electronic records - room for improvement. J Clin Epidemiol. 2021 Sep 12:S0895-4356(21)00291-2. doi: 10.1016/j.jclinepi.2021.09.011. Epub ahead of print.

McCarthy M, O'Keeffe L, Williamson PR, Sydes MR, Farrin A, Lugg-Widger F, Davies G, Avery K, Chan AW, Kwakkenbos L, Thombs BD, Watkins A, Hemkens LG, Gale C, Zwarenstein M, Langan SM, Thabane L, Juszczak E, Moher D, Kearney PM. A study protocol for the development of a SPIRIT extension for trials conducted using cohorts and routinely collected data (SPIRIT-ROUTINE). HRB Open Res. 2021 Jul 29;4:82. doi: 10.12688/hrbopenres.13314.1.

Nash DM, Bhimani Z, Rayner J, Zwarenstein M. Learning health systems in primary care: a systematic scoping review. BMC Fam Pract. 2021 Jun 23;22(1):126. doi: 10.1186/s12875-021-01483-z

Nicholls SG, Carroll K, Hey SP, Zwarenstein M, Zhang JZ, Nix HP, Brehaut JC, McKenzie JE, McDonald S, Weijer C, Fergusson DA, Taljaard M. A review of pragmatic trials found a high degree of diversity in design and scope, deficiencies in reporting and trial registry data, and poor indexing. J Clin Epidemiol. 2021 Sep;137:45-57. doi: 10.1016/j.jclinepi.2021.03.021. Epub 2021 Mar 28.

Nicholls SG, Carroll K, Goldstein CE, Brehaut JC, Weijer C, Zwarenstein M, Dixon S, Grimshaw JM, Garg AX, Taljaard M. Patient Partner Perspectives Regarding Ethically and Clinically Important Aspects of Trial Design in Pragmatic Cluster Randomized Trials for Hemodialysis. Can J Kidney Health Dis. 2021 Jul 26;8:20543581211032818. doi: 10.1177/20543581211032818.

Norton WE, Loudon K, Chambers DA, Zwarenstein M. Designing provider-focused implementation trials with purpose and intent: introducing the PRECIS-2-PS tool. Implement Sci. 2021 Jan 7;16(1):7. doi: 10.1186/s13012-020-01075-y.

Puchalski Ritchie LM, Kip EC, Mundeva H, van Lettow M, Makwakwa A, Straus SE, Hamid JS, Zwarenstein M, Schull MJ, Chan AK, Martiniuk A, van Schoor V. Process evaluation of an implementation strategy to support uptake of a tuberculosis treatment adherence intervention to improve TB care and outcomes in Malawi. BMJ Open. 2021 Jul 2;11(7):e048499. doi: 10.1136/bmjopen-2020-048499.

Stewart M, Fortin M, Brown JB, Ryan BL, Pariser P, Charles J, Pham TN, Boeckxstaens P, Reichert SM, Zou GY, Bhattacharya O, Katz A, Piccinini-Vallis H, Sampalli T, Wong ST, Zwarenstein M. Patient-centred innovation for multimorbidity care: a mixed-methods, randomised trial and qualitative study of the patients' experience.  Br J Gen Pract. 2021 Mar 26;71(705):e320-e330. doi: 10.3399/bjgp21X714293 

Zwarenstein M, Howie A. Blinding, pragmatism, and the PRECIS-2 tool for designing and assessing randomized trials. Eur J Clin Pharmacol. 2021 Jan 4. doi: 10.1007/s00228-020-03078-6. Epub ahead of print.

Al-Jaishi AA, McIntyre CW, Sontrop JM, Dixon SN, Anderson S, Bagga A, Benjamin D, Berry D, Blake PG, Chambers L, Chan PCK, Delbrouck N, Devereaux PJ, Ferreira-Divino LF, Goluch R, Gregor L, Grimshaw JM, Hanson G, Iliescu E, Jain AK, Lok CE, Mustafa RA, Nathoo B, Nesrallah GE, Oliver MJ, Pandeya S, Parmar MS, Perkins D, Presseau J, Rabin E, Sasal J, Shulman T, Sood MM, Steele A, Tam P, Tascona D, Wadehra D, Wald R, Walsh M, Watson P, Wodchis W, Zager P, Zwarenstein M, Garg AX. Major Outcomes With Personalized Dialysate TEMPerature (MyTEMP): Rationale and Design of a Pragmatic, Registry-Based, Cluster Randomized Controlled Trial. Can J Kidney Health Dis. 2020 Feb 5;7:2054358119887988. doi: 10.1177/2054358119887988. eCollection 2020.

Carlisle K, Felton-Busch C, Cadet-James Y, Taylor J, Bailie R, Farmer J, Passey M, Matthews V, Callander E, Evans R, Kelly J, Preston R, Redman-MacLaren M, Fox H, Esterman A, Zwarenstein M, Larkins S. WOmen's Action for Mums and Bubs (WOMB) Trial Protocol: A Non-randomized Stepped Wedge Implementation Trial of Participatory Women's Groups to Improve the Health of Aboriginal and Torres Strait Islander Mothers and Children in Australia. Front Public Health. 2020 Mar 18;8:73. doi: 10.3389/fpubh.2020.00073. eCollection 2020.

Donelle L, Regan S, Kerr M, Zwarenstein M, Bauer M, Warner G, Isaranuwatchai W, Zecevic A, Borycki E, Forbes D, Weeks L, Leipert B, Read E. Caring Near and Far by Connecting Community-Based Clients and Family Member/Friend Caregivers Using Passive Remote Monitoring: Protocol for a Pragmatic Randomized Controlled Trial. JMIR Res Protoc. 2020 Jan 10;9(1):e15027. doi: 10.2196/15027.

Espinet SD, Gotovac S, Knight S, Wissow L, Zwarenstein M, Lingard L, Steele M. Primary Care Practitioner Training in Child and Adolescent Psychiatry (PTCAP): A Cluster-Randomized Trial. Can J Psychiatry. 2020 May;65(5):319-329. doi: 10.1177/0706743719890161. Epub 2019 Dec 9.

Fitzpatrick M, Rac VE, Mitsakakis N, Abrahamyan L, Pechlivanoglou P, Chung S, Carcone SM, Pham B, Kendzerska T, Zwarenstein M, Gottschalk R, George C, Kashgari A, Krahn M. SIESTA - Home sleep study with BresoDx for obstructive sleep apnea: a randomized controlled trial. Sleep Med. 2020 Jan;65:45-53. doi:10.1016/j.sleep.2019.07.013. Epub 2019 Jul 22.

Hayward MN, Pace R, Zaran H, Dyck R, Hanley AJ, Green ME, Bhattacharyya O, Zwarenstein M, Emond J, Benoit C, Jebb ML, Harris SB; FORGE AHEAD Program Team. Closing the indigenous health gap in Canada: Results from the TransFORmation of IndiGEnous PrimAry HEAlthcare delivery (FORGE AHEAD) program. Diabetes Res Clin Pract. 2020 Apr;162:108066. doi: 10.1016/j.diabres.2020.108066. Epub 2020 Feb 8.

Kueper JK, Terry AL, Zwarenstein M, Lizotte DJ. Artificial Intelligence and Primary Care Research: A Scoping Review. Ann Fam Med. 2020;18(3):250‐258. doi:10.1370/afm.2518

Nicholls SG, Zwarenstein M, Hey SP, Giraudeau B, Campbell MK, Taljaard M. The importance of decision intent within descriptions of pragmatic trials. J Clin Epidemiol. 2020 Sep;125:30-37. doi:10.1016/j.jclinepi.2020.04.030. Epub 2020 May 15.

Nicholls SG, Zwarenstein M, Taljaard M. The Importance of Describing as Well as Defining Usual Care. (Comment on Misrepresenting "Usual Care" in Research: An Ethical and Scientific Error. Am J Bioeth. 2020 Jan;20(1):56-58. doi: 0.1080/15265161.2019.1687781.

Pfaff KA, Dolovich L, Howard M, Sattler D, Zwarenstein M, Marshall D. Unpacking 'The Cloud': A Framework for Implementing Public Health Approaches to Palliative Care. Health Promot Inc, 35 (1), 160-170 2020 Feb 1. doi: 10.1093/heapro/day123. Epub 2019 Jan 27.

Puchalski Ritchie LM, van Lettow M, Makwakwa A, Kip EC, Straus SE, Kawonga H, Hamid JS, Lebovic G, Thorpe KE, Zwarenstein M, Schull MJ, Chan AK, Martiniuk A, van Schoor V. Impact of a tuberculosis treatment adherence intervention versus usual care on treatment completion rates: results of a pragmatic cluster randomized controlled trial. Implement Sci. 2020 Dec 11;15(1):107. doi: 10.1186/s13012-020-01067-y.

Ryan BL, Allen B, Zwarenstein M, Stewart M, Glazier RH, Fortin M, Wetmore SJ, Shariff SZ. Multimorbidity and mortality in Ontario, Canada: A population-based retrospective cohort study. J Comorb. 2020 Aug 27;10:2235042X20950598. doi: 10.1177/2235042X20950598.

Shet AS, Zwarenstein M, Galanti MR. Extrapolation Pitfalls and Methodology Flaws in Curing Anemia via Parental Education and Counseling-Reply. Reply JAMA Pediatr. 2020 Mar 1;174(3):302. doi: 10.1001/jamapediatrics.2019.5054. Epub 2020 Jan 13.

Taljaard M, McDonald S, Nicholls SG, Carroll K, Hey SP, Grimshaw JM, Fergusson DA, Zwarenstein M, McKenzie JE. A search filter to identify pragmatic trials in MEDLINE was highly specific but lacked sensitivity. J Clin Epidemiol. 2020 Aug;124:75-84. doi: 10.1016/j.jclinepi.2020.05.003. Epub 2020 May 11.

Zwarenstein M, Thorpe K, Treweek S, Loudon K. PRECIS-2 for retrospective assessment of RCTs in systematic reviews: some thoughts on intention, dichotomization and applicability of RCTs. J Clin Epidemiol. 2020 Oct;126:202-206. doi:10.1016/j.jclinepi.2020.06.023. Epub 2020 Jun 19.  

Cheng I, Taylor D, Schull MJ, Zwarenstein M, Kiss A, Castren M, Brommels M, Yeoh M, Kerr F. Comparison of emergency department time performance between a Canadian and an Australian academic tertiary hospital. Emerg Med Australas. 2019 Feb 27. doi: 10.1111/1742-6723.13247. Epub ahead of print.

Nicholls SG, Carroll K, Zwarenstein M, Brehaut JC, Weijer C, Hey SP, Goldstein CE, Graham ID, Grimshaw JM, McKenzie JE, Fergusson DA, Taljaard M; Ethics of Pragmatic Trials project. The ethical challenges raised in the design and conduct of pragmatic trials: an interview study with key stakeholders. Trials. 2019 Dec 23;20(1):765. doi: 10.1186/s13063-019-3899-x.

Norton WE, Zwarenstein M, Czajkowski S, Kato E, O'Mara A, Shelburne N, Chambers DA, Loudon K. Building internal capacity in pragmatic trials: a workshop for program scientists at the US National Cancer Institute. Trials. 2019 Dec 27;20(1):779. doi: 10.1186/s13063-019-3934-y.

Ryan BL, Thorpe C, Zwarenstein M, Wickett J, Talukdar N, Boisvert L, Wetmore SJ. Building research culture and capacity in academic family medicine departments: Insights from a simulation workshop. Can Fam Physician. 2019 Jan;65(1):e38-e44. 

Shet AS, Zwarenstein M, Rao A, Jebaraj P, Arumugam K, Atkins S, Mascarenhas M, Klar N, Galanti MR. Effect of a Community Health Worker-Delivered Parental Education and Counseling Intervention on Anemia Cure Rates in Rural Indian Children: A Pragmatic Cluster Randomized Clinical Trial. JAMA Pediatr. 2019 Jul 22. doi: 10.1001/jamapediatrics.2019.2087. Epub ahead of print.

Yau M, Timmerman V, Zwarenstein M, Mayers P, Cornick RV, Bateman E, Fairall L. e-PC101: An electronic clinical decision support tool developed in South Africa for primary care in low-income and middle-income countries. BMJ Global Health. 2019 Feb 20;3(Suppl 5):e001093. doi: 10.1136/bmjgh-2018-001093. eCollection 2018.

Dainty KN, Golden BR, Hannam R, Webster F, Browne G, Mittmann N, Stern A, Zwarenstein M. A realist evaluation of value-based care delivery in home care: The influence of actors, autonomy and accountability. Soc Sci Med. 2018 Apr 6;206:100-109. doi: 10.1016/j.socscimed.2018.04.006. Epub ahead of print.

Booth R, Sinclair B, McMurray J, Strudwick G, Watson G, Ladak H, Zwarenstein M, McBride S, Chan R, Brennan L. Evaluating a Serious Gaming Electronic Medication Administration Record System Among Nursing Students: Protocol for a Pragmatic Randomized Controlled Trial. JMIR Res Protoc. 2018 May 28;7(5):e138. doi:10.2196/resprot.9601.

Fitzpatrick T, Perrier L, Shakik S, Cairncross Z, Tricco AC, Lix L, Zwarenstein M, Rosella L, Henry D. Assessment of Long-term Follow-up of Randomized Trial Participants by Linkage to Routinely Collected Data: A Scoping Review and Analysis. JAMA Netw Open. 2018 Dec 7;1(8):e186019. doi: 10.1001/jamanetworkopen.2018.6019.

Kwakkenbos L, Imran M, McCord KA, Sampson M, Fröbert O, Gale C, Hemkens LG, Langan SM, Moher D, Relton C, Zwarenstein M, Benchimol EI, Boutron I, Campbell MK, Erlinge D, Jawad S, Ravaud P, Rice DB, Sauve M, van Staa TP, Thabane L, Uher R, Verkooijen HM, Juszczak E, Thombs BD. Protocol for a scoping review to support development of a CONSORT extension for randomised controlled trials using cohorts and routinely collected health data. BMJ Open. 2018 Aug 5;8(8):e025266. doi:10.1136/bmjopen-2018-025266.

Ryan BL, Bray Jenkyn K, Shariff SZ, Allen B, Glazier RH, Zwarenstein M, Fortin M, Stewart M. Beyond the grey tsunami: a cross-sectional population-based study of multimorbidity in Ontario. Can J Public Health. 2018 Jul 18. doi:10.17269/s41997-018-0103-0. Epub ahead of print

Reeves S, Xyrichis A, Zwarenstein M. Teamwork, collaboration, coordination, and networking: Why we need to distinguish between different types of interprofessional practice. J Interprof Care, 2018 Jan 1; 32 (1):1-3, doi:10.1080/13561820.2017.1400150. Epub 2017 Nov 13.

Taljaard M, Weijer C, Grimshaw JM, Ali A, Brehaut JC, Campbell MK, Carroll K, Edwards S, Eldridge S, Forrest CB, Giraudeau B, Goldstein CE, Graham ID, Hemming K, Hey SP, Horn AR, Jairath V, Klassen TP, London AJ, Marlin S, Marshall JC, McIntyre L, McKenzie JE, Nicholls SG, Alison Paprica P, Zwarenstein M, Fergusson DA. Developing a framework for the ethical design and conduct of pragmatic trials in healthcare: a mixed methods research protocol. Trials. 2018 Sep 27;19(1):525. doi: 10.1186/s13063-018-2895-x.

Xyrichis A, Reeves S, Zwarenstein M. Examining the nature of interprofessional practice: An initial framework validation and creation of the InterProfessional Activity Classification Tool (InterPACT). J Interprof Care. 2018 Jul:32(4):416-425. doi: 10.1080/13561820.2017.1408576. Epub 2017 Dec 13.

Diamantouros A, Kiss A, Papastavros T, U D, Zwarenstein M, Geerts WH. The TOronto ThromboProphylaxis Patient Safety Initiative (TOPPS): A cluster randomised trial. Res Social Adm Pharm, 2017 Sep-Oct;13(5):997-1003. doi: 10.1016/j.sapharm.2017.05.015. Epub 2017 May 27.

Diamantouros A, Marchesano R, Geerts WH, Pennefather P, Zwarenstein M, Austin Z. Development and evaluation of a continuing pharmacy education (CPE) program in thrombosis management. Curr Pharm Teach Learn. 2017 Sep;9(5):911-917. doi: 10.1016/j.cptl.2017.05.008. Epub 2017 Jul 14.

Fitzpatrick T, Perrier L, Tricco AC, Straus SE, Jüni P, Zwarenstein M, Lix LM, Smith M, Rosella LC, Henry DA. Protocol for a scoping review of post-trial extensions of randomised controlled trials using individually linked administrative and registry data. BMJ Open. 2017 Feb 17;7(2):e013770.

Loudon K, Zwarenstein M, Sullivan F, Donnan P, Gágyor I, Hobbelen H, Althabe F, Krishnan JA, Treweek S. The PRECIS - 2 tool has good inter - rater reliability and reasonable discriminant validity. J Clin Epidemiol, 2017 Aug;88:113-121. doi: 10.1016/j.jclinepi.2017.06.001. Epub 2017 Jun 8.

Munce SEP, Graham ID, Salbach NM, Jaglal SB, Richards CL, Eng JJ, Desrosiers J, MacKay-Lyons M, Wood-Dauphinee S, Korner-Bitensky N, Mayo NE, Teasell RW, Zwarenstein M, Mokry J, Black S, Bayley M. Perspectives of health care professionals on the facilitators and barriers to the implementation of a stroke rehabilitation guidelines cluster randomized controlled trial. BMC Health Serv Res. 2017 Jun 26;17(1):440. doi: 10.1186/s12913-017-2389-7.

Petrella RJ, Gill DP, Zou G, De Cruz A, Riggin B, Bartol C, Danylchuk K, Hunt K, Wyke S, Gray CM, Bunn C, Zwarenstein M. Hockey Fans in Training: A Pilot Pragmatic Randomized Controlled Trial. Med Sci Sports Exerc. 2017 Jul 17. doi: 10.1249/MSS.0000000000001380.

Reeves S, Pelone F, Harrison R, Goldman J, Zwarenstein M. Interprofessional collaboration to improve professional practice and healthcare outcomes. Cochrane Database Syst Rev. 2017 Jun 22;6:CD000072. doi: 10.1002/14651858.CD000072.pub3.

Salbach NM, Wood-Dauphinee S, Desrosiers J, Eng JJ, Graham ID, Jaglal SB, Korner-Bitensky N, MacKay-Lyons M, Mayo NE, Richards CL, Teasell RW, Zwarenstein M, Bayley MT; Stroke Canada Optimization of Rehabilitation By Evidence – Implementation Trial (SCORE-IT) Team. Facilitated interprofessional implementation of a physical rehabilitation guideline for stroke in inpatient settings: process evaluation of a cluster randomized trial. Implement Sci. 2017 Aug 1;12(1):100. doi: 10.1186/s13012-017-0631-7.

Shet AS, Rao A, Jebaraj P, Mascarenhas M, Zwarenstein M, Galanti MR, Atkins S. Lay health workers perceptions of an anemia control intervention in Karnataka, India: a qualitative study. BMC Public Health. 2017 Sep 18;17(1):720. doi: 10.1186/s12889-017-4758-x.

Stewart M, Fortin M, with the PACE in MM Team, Belanger M, Bestard-Denomme L, Bhattacharyya O, Borges DS, Bouhali T, Brown JB, Charles J, Chouinard MC, Emond V, Gallagher F, Glazier RH, Hogg WE, Katz A, Loignon C, Pariser P, Pham TN, Piccinini-Vallis H, Reichert S, Ryan BL, Sampalli T, Sussman J, Thind A, Wodchis W, Wong ST, Zwarenstein MF, Couture M, Huras PW. Patient-Centred Innovations for Persons with Multimorbidity: funded evaluation protocol. CMAJ Open, 2017 May 9; 5 (2): E365-E372, doi: 10.9778/cmajo.20160097.

Wieland LS, Berman BM, Altman DG, Barth J, Bouter LM, D'Adamo CR, Linde K, Moher D, Mullins CD, Treweek S, Tunis S, van der Windt DA, Zwarenstein M, Witt C. Rating of Included Trials on the Efficacy-Effectiveness Spectrum (RITES): development of a new tool for systematic reviews. J Clin Epidemiol. 2017 Apr;84:95-104. doi: 10.1016/j.jclinepi.2017.01.010 Epub 2017 Feb 7.

Zwarenstein M, Treweek S, Loudon K. PRECIS-2 helps researchers design more applicable RCTs while CONSORT Extension for pragmatic trials helps knowledge users decide whether to apply them. J Clin Epidemiol. 2017 Apr;84:27-29. doi: 10.1016/j.jclinepi.2016.10.010.

Zwarenstein M. 'Pragmatic' and 'explanatory' attitudes to randomised trials. J R Soc Med. 2017 May;110(5):208-218. doi: 10.1177/0141076817706303.

Zwarenstein M, Shariff S, Mittmann N, Stern A, Dainty KN. A large cluster randomized trial of outcome-based pathways to improve home-based wound care. Trials. 2017 Aug 29;18(1):393. doi: 10.1186/s13063-017-2082-5.