Seminar Series: Dr. Rishi Ganesan

Trials and Triumphs: A Researcher's Love-Hate Relationship with Randomized Controlled Trials

Rishi Ganesan

Assistant Professor
Department of Paediatrics,
Department of Clinical Neurological Sciences
Schulich School of Medicine & Dentistry
Western University

Physician
Paediatric Critical Care Medicine
Children's Hospital
London Health Sciences Center

Western Institute for Neurosciences
Western University

Children's Hospital Research Institute
London Health Sciences Center Research Institute (LHSCRI)

Short Biography:
Dr. Rishi Ganesan is a paediatric critical care physician-researcher at the Children's Hospital - LHSC, and an Assistant Professor in the Depts. of Paediatrics and Clinical Neurological Sciences at the Schulich School of Medicine & Dentistry, Western University, London (ON), Canada. Dr. Ganesan's clinical-research training in paediatrics, critical care, neurology and neurocritical care is very unique and positions him well to be a leader in this space. He is passionate about improving diagnosis and treatment of altered states of cognition and consciousness in critically ill patients. His research program aims to improve long-term functional outcomes in critically ill children through the testing and validation of advanced electrical and functional neuroimaging tools for prediction and detection of pathological brain states. This line of work will empower bedside critical care providers with the tools, knowledge, and skills to identify evolving brain pathologies quickly and determine prognosis objectively in high-risk critically ill children with acquired brain injury. His program utilizes observational studies, randomized clinical trials and knowledge translation to achieve these goals.

Abstract:
Randomized controlled trials (RCTs) are often considered the gold standard in clinical research, but they come with their own set of advantages and disadvantages. Join us for an insightful talk where Dr. Rishi Ganesan delves into the strengths and pitfalls of randomized controlled trials (RCTs) through reflecting on his own research journey. Having been involved in RCTs across various countries and settings, Dr. Ganesan 's relationship with RCTs has been a rollercoaster of emotions. Initially enamored by their potential to provide clear, causal evidence, he then faced disillusionment due to high costs, and limited generalizability. However, after taking a detour into neuroscience, he has rediscovered his passion for a more nuanced approach to RCTs, balancing rigor with real-world applicability. This talk promises to offer valuable lessons and practical insights for researchers navigating the complex landscape of clinical trials.

Area of Research:
neuroprognostication, functional neuroimaging, critical care delirium, disorders of consciousness


Date: Friday, January 31
Time: 1:30 pm - 2:30 pm
Location: PHFM 3015 (Western Centre for Public Health and Family Medicine) or Zoom (request link by email  epibio@uwo.ca)