Seminar Series: Dr. Sebastian Fridman
London Stroke Registries: Opportunities and Challenges
Sebastian Fridman, MD, MPH
Assistant Professor
Department of Clinical Neurological Sciences
Schulich School of Medicine & Dentistry
Western University
Cross-Appointed Assistant Professor
Department of Epidemiology and Biostatistics
Schulich School of Medicine & Dentistry
Western University
Short Biography:
Sebastian Fridman is an MD and MPH. He completed his medical degree at the University of Buenos Aires, graduating with honors in 2003. He earned his MPH from Harvard University in 2016. Dr. Fridman completed his neurology residency at the French Hospital in Buenos Aires and pursued two fellowships in vascular neurology: the first at ENERI Medical Institute and the second at Western University in London, Ontario.
He co-coordinated the first comprehensive stroke unit in Argentina and helped develop the first mobile stroke unit with a CT scan in an ambulance. His research focuses on observational study designs, advanced research methods like AI in missing data, combinatorial meta-analysis, and stroke-related topics.
He is currently an Assistant Professor in Neurology and a stroke neurologist at London Health Science Centre University Hospital.
Abstract:
The London Ontario Stroke Registry (LOSR) has become a cornerstone for stroke research and quality improvement, offering a platform that supports a range of studies and initiatives. Initially designed for collecting comprehensive clinical data, LOSR has evolved into a powerful tool for both retrospective analyses and ongoing quality improvement efforts within the institution. It has served as the foundation for single-center retrospective studies that inform local practices and care strategies, as well as randomized trials conducted on the same platform to drive innovation in stroke treatment.
Furthermore, LOSR’s capacity extends to multicenter collaborations, enabling participation in international stroke registries and fostering partnerships aimed at addressing global challenges in stroke care. This presentation will explore how LOSR supports these diverse research activities and the future potential of the registry to drive clinical improvements, inform treatment decisions, and improve patient outcomes through data-driven insights.
In addition, the London Vascular Neuroradiology (LoVNeRa) project has been built on top of LOSR as a dedicated neuroimaging registry. LoVNeRa leverages advanced AI tools to analyze imaging data, providing new opportunities to predict outcomes and refine treatment approaches in stroke care. This initiative highlights the growing role of neuroimaging in shaping personalized stroke management and expanding the research horizons of LOSR.
Keywords:
Stroke, Acute stroke management, Neuroimaging, Observational Studies, Meta-analysis
Date: Friday, September 13
Time: 1:30 pm - 2:30 pm
Location: PHFM 3015 (Western Centre for Public Health and Family Medicine) or Zoom (link may be requested at EpiBio@uwo.ca)
